RecruitingNot ApplicableNCT07745920

Managing Depressive Symptoms in ADPKD

A Pilot Study for Managing Depressive Symptoms in Autosomal Dominant Polycystic Kidney Disease (ADPKD)


Sponsor

Mayo Clinic

Enrollment

105 participants

Start Date

Jun 12, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to evaluate the feasibility and effectiveness of Digital Neurotherapy (DNT) or Capacity Coaching (CC) for managing symptoms of depression and self reported pain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) compared to education alone.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Capacity Coaching, a behavioral approach called Digital Neuropathy, and others for people with autosomal dominant polycystic kidney disease. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALMayo Clinic-Approved Education

Education attention control will be administered by board certified health and wellness coaches via virtual coaching sessions.

BEHAVIORALDigital Neuropathy

The web-based system (REJUVENATE) consists of a set of cognitive exercises continuously and automatically adjusted in difficulty based on each user's performance to maintain the balance of challenge and success optimal to promote neuroplastic enhancement of target neural systems.

BEHAVIORALCapacity Coaching

Board certified health and wellness coaches will create a plan with subjects to use capacity, defined as patients' abilities and resources, to do self-management work.


Locations(1)

Mayo Clinic

Rochester, Minnesota, United States

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NCT07745920


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