RecruitingPhase 2NCT07761910

Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer

Sponsor

Indiana University

Enrollment

10 participants

Start Date

Sep 1, 2026

Study Type

INTERVENTIONAL

Conditions

Non-small Cell Lung Cancer Cardiotoxicity Locally Advanced Non-Small Cell Lung Cancer Radiation Therapy

Summary

Prospective clinical study designed to evaluate damage to the heart after receiving standard of care chemotherapy and radiation therapy for locally advanced Non-Small Cell Lung Cancer (NSCLC).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called 18F-Flurpiridaz, a medical device called Coronary CT Angiography (CCTA), and others for people with cardiotoxicity, locally advanced non-small cell lung cancer, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTPET/CT 18F-Flurpiridaz Rest/Stress Test

A two-phase, rest and regadenoson stress evaluated by 18F-Flurpiridaz PET/CT before and 3 months after SOC radiation treatment.

DEVICECoronary CT Angiography (CCTA)

Coronary computed tomographic angiography (CCTA) scan is a highly accurate noninvasive technique for detection of coronary artery plaque.

DRUG18F-Flurpiridaz

A two-phase, rest and regadenoson stress evaluated by 18F-Flurpiridaz PET/CT before and 3 months after SOC radiation treatment

Locations(1)

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Indianapolis, Indiana, United States

View Full Details on ClinicalTrials.gov

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NCT07761910

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