RecruitingNot ApplicableNCT07777627

Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries

Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation Surgeries: A Randomized Double-Blinded Study

Sponsor

Tanta University

Enrollment

90 participants

Start Date

Jul 1, 2026

Study Type

INTERVENTIONAL

Conditions

Postoperative Pain Placebo Intrathecal Morphine Intrathecal Dexmedetomidine Spine Fixation Surgeries

Summary

This study aims to compare the efficacy of intrathecal morphine and intrathecal dexmedetomidine in reducing pain following lumbar spine fixation surgeries.

Eligibility

Min Age: 21 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Intrathecal Dexmedetomidine, a drug called Intrathecal Morphine, and others for people with intrathecal dexmedetomidine, intrathecal morphine, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 21 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGIntrathecal Morphine

Patients will receive intrathecal morphine (0,3 mg) in 2 ml normal saline at the end of the operation through a 25G spinal needle through the lumbar intervertebral space (L3-L4 or L4-L5).

DRUGIntrathecal Dexmedetomidine

Patients will receive intrathecal 2 ml normal saline at the end of the operation through a 25G spinal needle through the lumbar intervertebral space (L3-L4 or L4-L5).

DRUGNormal Saline

Patients will receive intrathecal 2 ml normal saline at the end of the operation through a 25G spinal needle through the lumbar intervertebral space (L3-L4 or L4-L5).