RecruitingPhase 3NCT07780669

A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-1)

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study of the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants 40 to 80 Years of Age With Moderate to Very Severe COPD (PERSIST COPD-1)


Sponsor

GlaxoSmithKline

Enrollment

624 participants

Start Date

Aug 27, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The study primarily aims to demonstrate the superiority of GSK5784283 as an add-on therapy compared to placebo in reducing the annualized rate of moderate and severe chronic obstructive pulmonary disease (COPD) exacerbations.


Eligibility

Min Age: 40 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called GSK5784283, a drug called Placebo, and others for people with pulmonary disease, chronic obstructive. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 40 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGGSK5784283

GSK5784283 will be administered.

DRUGPlacebo

Placebo will be administered.

DRUGStandard of care

Standard of care will be administered.


Locations(2)

GSK Investigational Site

Doral, Florida, United States

GSK Investigational Site

Lake Charles, Louisiana, United States

View Full Details on ClinicalTrials.gov

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NCT07780669


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