RecruitingNot ApplicableNCT07803601

Effect of Intravenous Magnesium on Postoperative Systemic Inflammatory Response in Patients Undergoing Colorectal Cancer Surgery

Sponsor

Ain Shams University

Enrollment

52 participants

Start Date

Mar 1, 2026

Study Type

INTERVENTIONAL

Conditions

Post Operative Pain Post Operative Inflammatory Marker Levels

Summary

The aim of this study is to detect the effect of intraoperative intravenous magnesium sulfate on postoperative systemic inflammatory response by serum inflammatory parameters as CRP, WBCS and neutrophil count.

Eligibility

Min Age: 35 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Magnesium sulfate (MgSO4) and a drug called Normal Saline for people with post operative inflammatory marker levels and post operative pain. The study is currently recruiting participants at 1 location. People eligible for this study include aged 35 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMagnesium sulfate (MgSO4)

After the induction of anesthesia, the patients will receive loading intravenous magnesium sulfate (50mg/kg over 20 minutes) and maintenance (15mg/kg/hr) till the end of surgery.

DRUGNormal Saline

The patients will receive the same normal saline volume for loading and maintenance.

Locations(1)

Ain shams university

Cairo, Abbassia, Egypt

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NCT07803601

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