RecruitingNCT07810959

Breast and Vascular Effects of Menopausal Hormone Therapy in Postmenopausal Women

Prospective Evaluation of the Effects of Menopausal Hormone Therapy on Breast Imaging Findings and Carotid Intima-Media Thickness in Postmenopausal Women

Sponsor

Sanliurfa Mehmet Akif Inan Education and Research Hospital

Enrollment

120 participants

Start Date

Jun 1, 2026

Study Type

OBSERVATIONAL

Conditions

Menopause

Summary

This prospective, single-center, observational controlled cohort study aims to evaluate the effects of menopausal hormone therapy (MHT) on breast imaging findings and carotid intima-media thickness in postmenopausal women. A total of 120 postmenopausal women will be enrolled. Participants will be observed in two groups according to their clinical management: women receiving systemic menopausal hormone therapy (n=70) and women not receiving systemic menopausal hormone therapy (n=50). Breast imaging findings, breast density, menopausal symptoms, endometrial findings, cardiometabolic parameters, and carotid intima-media thickness will be prospectively evaluated during a 12-month follow-up period.

Eligibility

Sex: FEMALEMin Age: 45 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Menopausal Hormone Therapy for people with menopause. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMenopausal Hormone Therapy

Systemic menopausal hormone therapy prescribed as part of routine clinical care according to individual clinical indications. Treatment is not assigned by the study protocol.