RecruitingNCT07823387

Intra-Abdominal Pressure Changes During Continuous Renal Replacement Therapy in Critically Ill Patients

Prospective Evaluation of Intra-Abdominal Pressure Changes in Critically Ill Patients Receiving Continuous Renal Replacement Therapy


Sponsor

Bursa Yuksek Ihtisas Training and Research Hospital

Enrollment

95 participants

Start Date

Jul 20, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This prospective observational study will evaluate changes in intra-abdominal pressure in critically ill adult patients receiving continuous renal replacement therapy in the intensive care unit. Intra-abdominal pressure will be measured through the urinary bladder at predefined time points during therapy. The study will also assess the relationship between intra-abdominal pressure changes and clinical variables, including fluid balance, hemodynamic parameters, vasopressor requirement, urine output, severity scores, duration of renal replacement therapy, intensive care unit and hospital length of stay, and 30-day survival. No additional treatment or therapeutic intervention will be administered for research purposes.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age 18 years or older
  • Admission to the intensive care unit
  • Receiving continuous renal replacement therapy (CRRT)
  • Presence of an indwelling urinary (Foley) catheter for intra-abdominal pressure measurement

Exclusion Criteria7

  • Pregnancy
  • Open abdominal wound or open abdomen
  • Neurogenic bladder
  • History of bladder surgery
  • Pelvic hematoma
  • Pelvic fracture
  • Presence of an intra-abdominal mass or other anatomical/technical condition that may compromise the reliability of intravesical pressure measurement

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Interventions

PROCEDUREIntravesical Intra-abdominal Pressure Measurement

Intravesical intra-abdominal pressure will be measured via the existing urinary catheter at baseline and at 6, 12, 24, 48, and 72 hours after initiation of continuous renal replacement therapy (CRRT). Measurements will be performed for study data collection only. No therapeutic intervention or modification of routine clinical management will be undertaken based solely on the study measurements.


Locations(1)

SBÜ Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi

Bursa, Bursa, Turkey (Türkiye)

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NCT07823387


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