Alcohol Use Disorder (AUD) Clinical Trials

34 recruiting

Alcohol Use Disorder (AUD) Trials at a Glance

33 actively recruiting trials for alcohol use disorder (aud) are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 12 trials, with the heaviest enrollment activity in Providence, Dresden, and Spokane. Lead sponsors running alcohol use disorder (aud) studies include Yale University, Washington State University, and Pharmacotherapies for Alcohol and Substance Use Disorders Alliance.

Browse alcohol use disorder (aud) trials by phase

Treatments under study

About Alcohol Use Disorder (AUD) Clinical Trials

Looking for clinical trials for Alcohol Use Disorder (AUD)? There are currently 34 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Alcohol Use Disorder (AUD) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Alcohol Use Disorder (AUD) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 33 trials

Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+7 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting
Phase 1

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Alcohol Use Disorder (AUD)Alcohol-Related DisordersAlcohol Use
Yale University63 enrolled1 locationNCT06070649
Recruiting
Phase 1Phase 2

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

Healthy VolunteersAlcohol Use Disorder (AUD)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)180 enrolled1 locationNCT06484075
Recruiting
Phase 2

LSD Treatment for Persons With Alcohol Use Disorder

Alcohol Use Disorder (AUD)
Felix Mueller128 enrolled2 locationsNCT05474989
Recruiting
Not Applicable

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

Alcohol DrinkingAlcohol Use DisorderSubstance Use+2 more
Medical University of South Carolina86 enrolled1 locationNCT04998916
Recruiting
Not Applicable

Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community

Substance Use Disorder (SUD)Alcohol Use Disorder (AUD)Nicotine Addiction
Sigmund Freud PrivatUniversitat100 enrolled3 locationsNCT06803706
Recruiting
Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide

HIVAlcohol Use Disorder (AUD)
Yale University30 enrolled1 locationNCT07040592
Recruiting
Phase 2

Alpha-1 Blockade for Alcohol Use Disorder (AUD)

Alcohol Use Disorder (AUD)
Brown University184 enrolled1 locationNCT04135846
Recruiting
Phase 2

Probenecid Administration for Alcohol Craving and Consumption

Alcohol ConsumptionAlcohol Use Disorder (AUD)Craving
Brown University120 enrolled1 locationNCT07118618
Recruiting
Not Applicable

Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder

Substance Use Disorder (SUD)Alcohol Use Disorder (AUD)Cocaine Use Disorder (CUD)
University of Bern210 enrolled1 locationNCT07071779
Recruiting
Phase 1

Diclofenac Dose Response Study

Alcohol Use Disorder (AUD)Alcohol-Related Disorders
University of Maryland, Baltimore24 enrolled1 locationNCT06636227
Recruiting
Phase 2

Study of Tirzepatide for Recovery and Alcohol Use Management

Alcohol Use Disorder (AUD)
Brigham and Women's Hospital20 enrolled2 locationsNCT06727331
Recruiting
Not Applicable

Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building

PTSDAlcohol Use Disorder (AUD)
University of Rhode Island80 enrolled1 locationNCT07217795
Recruiting
Phase 2

Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder

AlcoholismAlcohol Use Disorder (AUD)Alcohol Abuse/Dependence
Dr. med. Marcus Herdener75 enrolled1 locationNCT06969937
Recruiting
Not Applicable

Combining a Smartphone App With Medications to Manage Heavy Drinking

Alcohol Use Disorder (AUD)
VA Office of Research and Development330 enrolled15 locationsNCT06303778
Recruiting
Phase 1

Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study

Post Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance10 enrolled1 locationNCT06335407
Recruiting
Not Applicable

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design

AlcoholismAlcohol DrinkingBinge Drinking+3 more
University of Illinois at Urbana-Champaign200 enrolled2 locationsNCT07125534
Recruiting
Phase 2

Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)

PTSDAlcohol Use Disorder (AUD)
Nathan Brashares Sackett40 enrolled1 locationNCT06853912
Recruiting
Not Applicable

Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder

Alcohol Use Disorder (AUD)
Centre Hospitalier Universitaire de Nīmes168 enrolled7 locationsNCT04598399
Recruiting
Phase 1

Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers

Heavy DrinkerAlcohol ConsumptionAlcohol Use Disorder (AUD)
Yale University63 enrolled2 locationsNCT06136195