RecruitingNot ApplicableNCT07830225

A Pilot Study of ctDNA-Guided Immune Checkpoint Inhibitor Duration in Patients With Advanced Melanoma.


Sponsor

Rutgers, The State University of New Jersey

Enrollment

35 participants

Start Date

Sep 3, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This is a phase II pilot study evaluating the use of circulating tumor DNA (ctDNA) to guide the optimal duration of standard of care immune checkpoint inhibitor (ICI) therapy in patients with unresectable and/or metastatic melanoma who have radiographic evidence of disease control and/or response to treatment.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying A Pilot Study of ctDNA-guided immune checkpoint inhibitor duration in patients with advanced melanoma for people with melanoma (skin cancer). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERA Pilot Study of ctDNA-guided immune checkpoint inhibitor duration in patients with advanced melanoma

This is a phase II pilot study evaluating the use of circulating tumor DNA (ctDNA) to guide the optimal duration of standard of care immune checkpoint inhibitor (ICI) therapy in patients with unresectable and/or metastatic melanoma who have radiographic evidence of disease control and/or response to treatment.


Locations(1)

Rutgers Cancer Institute

New Brunswick, New Jersey, United States

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NCT07830225


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