RecruitingNot ApplicableNCT07831278

Training Independent Muscle Activation From a Common Source


Sponsor

Brigham and Women's Hospital

Enrollment

10 participants

Start Date

Sep 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

In this study, the investigators are evaluating a new surgical technique that may allow participants to control their muscles in a new way after their amputation or revision surgery. The investigators are looking for people who have limb amputation or require a revision operation to a previous amputation. Participants must be over 18 and younger than 65, willing to begin participation within two weeks of their surgery, and be willing to travel regularly to Boston. In this study, participants will have a modified revision procedure on their amputated limb or a modified amputation procedure, followed by a series of follow up visits in clinic and to a gait lab at Harvard. Participants will also use a wearable device on their limb at home to complete daily training tasks and games.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying amputation or revision procedure with additional RPNI construction for people with amputation. The study is currently recruiting participants at 2 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREamputation or revision procedure with additional RPNI construction

amputation or revision procedure in which additional RPNIs (regenerative peripheral nerve interfaces) are created beyond what would be included in a standard care procedure


Locations(2)

Brigham and Women's Hospital

Boston, Massachusetts, United States

Harvard University

Cambridge, Massachusetts, United States

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NCT07831278


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