Acute appendicitis Clinical Trials

8 recruitingLast updated: June 20, 2026

There are 8 actively recruiting acute appendicitis clinical trials across 8 countries. Studies span Not Applicable, Phase 3, Phase 4. Top locations include Amiens, France, Columbus, Ohio, United States, Fuzhou, Jiangxi, China. Updated daily from ClinicalTrials.gov.


Acute appendicitis Trials at a Glance

8 actively recruiting trials for acute appendicitis are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Amiens, Columbus, and Fuzhou. Lead sponsors running acute appendicitis studies include Centre Hospitalier Universitaire, Amiens, Intuitive Surgical, and A.O. Ospedale Papa Giovanni XXIII.

Browse acute appendicitis trials by phase

Treatments under study

About Acute appendicitis Clinical Trials

Looking for clinical trials for Acute appendicitis? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute appendicitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute appendicitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

Retrospective Acute Care Appendectomy Study

Acute appendicitis
Intuitive Surgical1,000 enrolled3 locationsNCT06624215
Recruiting

Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis

Acute appendicitis
Sanliurfa Education and Research Hospital200 enrolled1 locationNCT07496723
Recruiting
Not Applicable

Early vs Conventional Enteral Nutrition After Uncomplicated Paediatric Open Appendectomy

Uncomplicated Acute Appendicitis in Children
Shaikh Zayed Hospital, Lahore88 enrolled1 locationNCT07016919
Recruiting

Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children

Acute appendicitisAbdominal Pain (AP)Acute Appendicitis With Rupture
KBC Split100 enrolled1 locationNCT07008092
Recruiting
Not Applicable

Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial

Acute appendicitishand, foot and mouth diseasePneumococcal Pneumonia+2 more
Southern Medical University, China459 enrolled3 locationsNCT06699433
Recruiting
Phase 4

Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy

Acute appendicitisMultimodal AnalgesiaOpioid Consumption+1 more
Medical University of Warsaw188 enrolled1 locationNCT06563349
Recruiting
Phase 3

The Value of Post-operative Antibiotic Therapy After Laparoscopic Appendectomy for Complicated Acute Appendicitis (Other Than for Generalized Peritonitis)

Complicated Acute Appendicitis
Centre Hospitalier Universitaire, Amiens1,476 enrolled1 locationNCT03688295
Recruiting

Web-based International Register of Emergency Surgery and Trauma

Post-operative complicationsAcute diverticulitisAcute appendicitis+12 more
A.O. Ospedale Papa Giovanni XXIII10,000 enrolled1 locationNCT03643718