Trauma Clinical Trials

81 recruitingLast updated: May 4, 2026

Trauma Trials at a Glance

814 actively recruiting trials for trauma are listed on ClinicalTrialsFinder across 6 cities in 62 countries. The largest study group is Not Applicable with 436 trials, with the heaviest enrollment activity in Houston, New York, and Boston. Lead sponsors running trauma studies include VA Office of Research and Development, Karolinska Institutet, and Johns Hopkins University.

Treatments under study

About Trauma Clinical Trials

Looking for clinical trials for Trauma? There are currently 81 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Trauma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Trauma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 814 trials

Recruiting
Phase 2

Treating Spinal Cord Injury With Early Normobaric Hyperoxia

Traumatic Spinal Cord Injuries
University of Florida12 enrolled1 locationNCT07465302
Recruiting
Not Applicable

Onyx™ Liquid Embolic IDE Clinical Study

TraumaUlcerGI Bleed+2 more
Medtronic Endovascular119 enrolled16 locationsNCT06742801
Recruiting
Not Applicable

Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.

Traumatic Brain Injury
NYU Langone Health150 enrolled1 locationNCT04349852
Recruiting

A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

Traumatic Brain Injury
Hoffmann-La Roche2,000 enrolled12 locationsNCT07455136
Recruiting
Phase 3

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

PTSD - Post Traumatic Stress Disorder
Senseye, Inc.1,900 enrolled6 locationsNCT07280065
Recruiting
Not Applicable

Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel

DepressionAnxietyPosttraumatic Stress
University of Regina300 enrolled1 locationNCT04335487
Recruiting
Not Applicable

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

SleepMild Traumatic Brain InjurySleep Architecture+1 more
University of Missouri-Columbia15 enrolled1 locationNCT07385105
Recruiting
Not Applicable

Game Intervention for Resilience

Chronic StressTrauma Exposure
The University of Hong Kong60 enrolled1 locationNCT07235696
Recruiting

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Healthy VolunteerTobacco Use DisorderMigraine+7 more
Yale University200 enrolled2 locationsNCT06624137
Recruiting
Not Applicable

Psychotherapy Effects on Reward Processing in PTSD

Post Traumatic Stress DisorderAnhedoniaPTSD+3 more
University of Texas at Austin120 enrolled1 locationNCT06096740
Recruiting
Phase 2

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

Posttraumatic Stress DisorderPosttraumatic Headache
Northwestern University175 enrolled3 locationsNCT06608277
Recruiting
Not Applicable

Women Focused Encounters for Resilience Independence Strength and Eudaimonia

HIV InfectionsTraumaSubstance Use+1 more
University of California, San Diego300 enrolled1 locationNCT06216600
Recruiting
Not Applicable

Non-invasive BCI-controlled Assistive Devices

Traumatic Brain InjuryHealthyMovement Disorders+6 more
University of Texas at Austin100 enrolled1 locationNCT05183152
Recruiting
Not Applicable

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

DepressionMild Traumatic Brain InjuryConcussion, Brain
University of California, San Diego72 enrolled1 locationNCT05682677
Recruiting
Not Applicable

Effect of Semi-elemental Enteral Nutrition on Gastrointestinal Tolerance in Patients With Traumatic Brain Injury.

Traumatic Brain InjuryNeurocritical CareEnteral Feeding Intolerance
Tang-Du Hospital100 enrolled1 locationNCT07092423
Recruiting
Not Applicable

rTMS for Military TBI-related Depression

Depressive SymptomsConcussionMild Traumatic Brain Injury
Henry M. Jackson Foundation for the Advancement of Military Medicine198 enrolled3 locationsNCT05426967
Recruiting
Not Applicable

Group-based Stabilization and Skill Training for Patients With Lasting Posttraumatic Reactions in Mental Health Care

Stress Disorders, Post-TraumaticMental DisordersTrauma and Stressor Related Disorders
St. Olavs Hospital160 enrolled1 locationNCT03887559
Recruiting

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

TBITBI (Traumatic Brain Injury)Hemodynamic Instability+1 more
Children's Hospital Los Angeles1,000 enrolled1 locationNCT06195345
Recruiting

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Healthy ControlSchizophreniaPost Traumatic Stress Disorder+4 more
Yale University100 enrolled1 locationNCT01730781
Recruiting

Evaluation of the SCALED (SCaling AcceptabLE cDs)

Traumatic Brain InjuryVenous Thromboembolism
University of Minnesota15,000 enrolled1 locationNCT05628207