Trauma Clinical Trials

1,009 recruitingLast updated: July 17, 2026

There are 1,009 actively recruiting trauma clinical trials across 66 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include New York, New York, United States, Boston, Massachusetts, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Trauma Trials at a Glance

1,009 actively recruiting trials for trauma are listed on ClinicalTrialsFinder across 6 cities in 66 countries. The largest study group is Not Applicable with 532 trials, with the heaviest enrollment activity in New York, Boston, and Houston. Lead sponsors running trauma studies include VA Office of Research and Development, The University of Texas Health Science Center at San Antonio, and Karolinska Institutet.

Treatments under study

About Trauma Clinical Trials

Looking for clinical trials for Trauma? There are currently 87 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Trauma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Trauma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,009 trials

Recruiting
Not Applicable

Evaluating Treatments for Suicidal Veterans With PTSD

Post Traumatic Stress Disorder (PTSD)Self-directed Violence
VA Office of Research and Development125 enrolled4 locationsNCT05974631
Recruiting
Phase 2

Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury

Traumatic Brain Injury
Hope Biosciences LLC51 enrolled2 locationsNCT05951777
Recruiting
Not Applicable

Community-based Implementation of Online EmReg

Traumatic Brain InjuryEmotion Regulation
Icahn School of Medicine at Mount Sinai50 enrolled1 locationNCT05933629
Recruiting
Not Applicable

MentalGym™ and NeuroBrave™ Guided Wearable-Assisted Physiology Regulation Training for PTSD (PRTP)

PTSD - Post Traumatic Stress Disorder
NeuroBrave ltd.80 enrolled1 locationNCT07462312
Recruiting
Not Applicable

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

Post Traumatic Stress Disorder (PTSD)Opioid-use DisorderIntimate Partner Violence (IPV)
Yale University532 enrolled3 locationsNCT07115030
Recruiting
Not Applicable

Resolving Early Life Stress: Psychotherapy Outcomes and Neurobiology in Complex Depression

Depression - Major Depressive DisorderChildhood Traumas
St. Joseph's Healthcare Hamilton50 enrolled1 locationNCT07250893
Recruiting
Not Applicable

Stepped Care for Posttraumatic Stress Disorder Study

Post Traumatic Stress Disorder
Boston Medical Center428 enrolled1 locationNCT06947538
Recruiting
Not Applicable

Walk With Me (WWM) for Perinatal Grief

MiscarriagePost Traumatic Stress DisorderSuicidal Ideation+3 more
Oregon Research Behavioral Intervention Strategies, Inc.300 enrolled2 locationsNCT07011940
Recruiting
Not Applicable

The Effect of Early Intervention on the Incidence of Posttraumatic Stress Disorder After Intensive Care Hospitalization Due to Sepsis

SepsisPTSD - Post Traumatic Stress DisorderICU
Barzilai Medical Center60 enrolled1 locationNCT07707765
Recruiting
Phase 3

Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury

Traumatic Brain InjuryMilitary Operations
University of South Florida420 enrolled1 locationNCT06581003
Recruiting
Not Applicable

Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder

Post Traumatic Stress Disorder
University of Wisconsin, Madison180 enrolled1 locationNCT06341413
Recruiting
Phase 3

Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major Depressive Disorder

Post Traumatic Stress Disorder (PTSD)Major Depressive Disorder
Khyber Medical University Peshawar60 enrolled3 locationsNCT07703722
Recruiting
Not Applicable

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

InsomniaTraumatic Brain InjuryDepression+7 more
Johns Hopkins University360 enrolled5 locationsNCT05663034
Recruiting
Not Applicable

TMS for PTSD in Youth

Post Traumatic Stress Disorder (PTSD)
The University of Texas Health Science Center at San Antonio20 enrolled1 locationNCT07401225
Recruiting

Lidocaine Infusion Treatment for Subarachnoid Hemorrhage Headaches

HeadacheSubarachnoid; Hemorrhage, Nontraumatic
University of Kansas Medical Center20 enrolled1 locationNCT06582810
Recruiting
Not Applicable

Clinical Outcomes Study of the Nexel Total Elbow

Degenerative ArthritisElbow Joint DestructionPost-traumatic Lesions+7 more
Zimmer Biomet134 enrolled11 locationsNCT02469662
Recruiting

Microbiome Dysfunction in Surgical Intensive Care Unit Survivors

Sepsis, Trauma Injury
University of Florida468 enrolled1 locationNCT05357170
Recruiting
Phase 2

Preliminary Effectiveness of Individual and Group MDMA-assisted Therapy for Israeli Veterans With PTSD and Moral Injury.

Post Traumatic Stress DisorderMoral InjuryMDMA ('Ecstasy')
HaEmek Medical Center, Israel60 enrolled1 locationNCT05732155
Recruiting
Phase 3

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

Mild Traumatic Brain InjuryAdult Growth Hormone Deficiency
VA Office of Research and Development172 enrolled16 locationsNCT04867317
Recruiting
Not Applicable

Cognitive Rehabilitation for Victims of War and Related Traumas With Traumatic Brain Injury and Cognitive Impairment

TBI (Traumatic Brain Injury)Cognitive Symptoms
Massachusetts General Hospital50 enrolled1 locationNCT06839079