Phase 2 Acute Lymphoblastic Leukaemia Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 1Phase 2

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

Acute Lymphoblastic LeukaemiaAcute Myeloid Leukaemia
AstraZeneca84 enrolled30 locationsNCT07155226
Recruiting
Phase 2

Efficacy of Low-dose Venetoclax With Itraconazole + TACL for R/R ALL Patients

Philadelphia Chromosome Negative ALLAcute Lymphobkastic LeukemiaAcute Lymphoblastic Leukaemia Recurrent
Hospital Universitario Dr. Jose E. Gonzalez12 enrolled1 locationNCT07039877
Recruiting
Phase 2Phase 3

Intravenous Autologous CD19 CAR-T Cells for R/R B-ALL

Relapsed B Acute Lymphoblastic LeukaemiaRefractory B Acute Lymphoblastic Leukaemia
National University of Malaysia10 enrolled1 locationNCT03937544
Recruiting
Phase 2

Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial

Acute Myeloid LeukemiaChronic Myeloid LeukemiaMyelodysplastic Syndrome+3 more
Imperial College London50 enrolled8 locationsNCT06355583
Recruiting
Phase 2Phase 3

Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Acute Lymphoblastic Leukaemia
St. Anna Kinderkrebsforschung1,800 enrolled119 locationsNCT01949129
Recruiting
Phase 2

A multi-centre phase II, Australian and New Zealand, exploratory study of amendments to conditioning regimens in haplo-identical stem cell transplantation

transformed AML/ MDSMyeloproliferative DisordersHodgkin's Disease+4 more
St Vincent's Hospital, Sydney127 enrolled10 locationsACTRN12622001232729
Active
Phase 2

ALL09 - SUbstitute BLinatumomab to Improve Minimal Residual Disease Eradication in Adolescents and Young Adults with Acute Lymphoblastic Leukaemia – The SUBLIME Study

Acute Lymphoblastic Leukaemia
Australasian Leukaemia and Lymphoma Group55 enrolled16 locationsACTRN12618001734257
Recruiting
Phase 2

A phase II study of haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide as Graft versus Host Disease (GVHD) prophylaxis

Non Hodgkin's Disease in remissionAcute Myeloid Leukaemia in first or second complete remissionacute Lymphoblastic Leukaemia in first or second complete remission+7 more
St Vincent's Hospital Sydney70 enrolled6 locationsACTRN12617000151336
Active
Phase 2

BLAM- A phase IIb study of Blinatumomab + Cytarabine (AraC) and Methotrexate in adult B-precursor Acute Lymphoblastic Leukaemia

newly diagnosed acute lymphoblastic leukaemia
Australasian Leukaemia and Lymphoma Group30 enrolled10 locationsACTRN12617000084381
Withdrawn
Phase 2

A phase I/II clinical study of deliverability and efficacy of high dose lenalidomide for the treatment of adult patients with acute lymphoblastic leukaemia

Acute Lymphoblastic Leukaemia
Dr Sushrut Patil9 enrolled1 locationACTRN12613000993796
Completed
Phase 2

Dasatinib plus Chemotherapy in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia

Philadelphia Chromosone-Positive Acute Lymphoblastic Leukaemia (Ph+ ALL)
Australasian Leukaemia and Lymphoma Group (ALLG)20 enrolled1 locationACTRN12607000609459