Phase 1 Adenoma Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 17 of 7 trials

Recruiting
Phase 1Phase 2

Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis
Recursion Pharmaceuticals Inc.67 enrolled17 locationsNCT05552755
Recruiting
Phase 1

Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

Colorectal CarcinomaFamilial Adenomatous PolyposisColorectal Adenomatous Polyp+1 more
National Cancer Institute (NCI)36 enrolled5 locationsNCT05630794
Recruiting
Phase 1Phase 2

Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma

Colorectal Cancer (CRC)Metastatic Colorectal Carcinoma (mCRC)Adenomatous Polyposis Coli (APC) Gene Mutation+1 more
HonorHealth Research Institute126 enrolled1 locationNCT07463599
Recruiting
Phase 1

Use of [18F] Fluoroethyl-L-tyrosine PET/MRI for Identifying Small Functional Pituitary Adenomas

Pituitary Adenoma
Mayo Clinic5 enrolled1 locationNCT07456878
Recruiting
Phase 1

Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors

Colorectal AdenomaColorectal Cancer Prevention
Massachusetts General Hospital20 enrolled1 locationNCT07095517
Recruiting
Phase 1

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors

MelanomaSolid TumorSolid Tumor, Adult+3 more
Rise Therapeutics LLC33 enrolled1 locationNCT06398418
Recruiting
Phase 1Phase 2

Application of Al18F-NOTA-Pentixafor PET/CT for Primary Aldosteronism

Primary AldosteronismPrimary Aldosteronism Due to Aldosterone Producing Adenoma
Peking Union Medical College Hospital150 enrolled1 locationNCT06773663