Phase 4 Adults Clinical Trials
23 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 23 trials
Recruiting
Phase 4
Longitudinal Tracking of Bone Marrow Plasma Cell Responses to Licensed Human Vaccines
Healthy AdultsImmunology
Washington University School of Medicine25 enrolled1 locationNCT07493460
Recruiting
Phase 4
Comparing Dynamic Navigation to Static Navigation in the Implant Placement
Healthy AdultsDental ImplantAccuracy
Ain Shams University20 enrolled1 locationNCT07291336
Recruiting
Phase 4
Investigation of Locus Coeruleus Function in Sustained Attention
Attention - no Condition is Being Assessed - Healthy Adults
University of California, Davis40 enrolled1 locationNCT06041048
Recruiting
Phase 4
Sleep Apnea in Elderly
Elderly adultsSleep Apnea
VA Office of Research and Development100 enrolled1 locationNCT02703220
Recruiting
Phase 4
Characterizing the Human Airway Immune Response to FluMist Vaccination
Healthy Young AdultsInfluenza VaccinesInfluenza Vaccine Response
Washington University School of Medicine30 enrolled1 locationNCT07177417
Recruiting
Phase 4
Oral vs IV Sedation for Cataract Surgery in Older Adults
Older AdultsSedationPerioperative Care+2 more
University of California, San Francisco20 enrolled1 locationNCT07154147
Recruiting
Phase 4
Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery
EsketamineDexmedetomidineAdults+2 more
Peking University First Hospital476 enrolled1 locationNCT06859892
Recruiting
Phase 4
Long Acting Cabotegravir Plus Rilpivirine in People Living with HIV-1 Aged ≥ 60 Years for 24 Months.
HIV-1 Infected Adults with Controlled Viremia
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia120 enrolled8 locationsNCT06646562
Completed
Phase 4
Pilot study of a branded (marketed) formulation betamethasone dipropionate called Diprosone® OV ointment applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.
Diprosone OV ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12623001181695
Completed
Phase 4
Pilot study of a branded (marketed) formulation betamethasone dipropionate called Diprosone® ointment applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.
Diprosone ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12623001179628
Completed
Phase 4
Pilot study of a branded (marketed) formulation betamethasone dipropionate called Diprosone® cream applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.
Diprosone cream is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12623000887673
Completed
Phase 4
Pilot study of a branded (marketed) formulation methylprednisolone aceponate called Advantan fatty ointment applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.
Advantan fatty ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12623000272695
Completed
Phase 4
Pilot study of a branded (marketed) formulation methylprednisolone aceponate called Advantan ointment applied to the skin in healthy male and female volunteers to determine the appropriate dose duration (ED50) for use in a pivotal in vivo bioequivalence study.
Advantan ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12622001295730
Completed
Phase 3Phase 4
A randomised double-blind placebo-controlled study to evaluate the effect of curcumin on BDNF levels in otherwise healthy adults.
Brain-Derived Neurotrophic Factor in healthy adults
RDC Global Pty Ltd70 enrolled1 locationACTRN12621000104853
Completed
Phase 4
Pilot study of Advantan fatty ointment applied to the skin in Healthy male and female volunteers.
Advantan fatty ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited12 enrolled1 locationACTRN12619000510145
Recruiting
Phase 4
The impact of Clonidine, a pharmacological treatment for attention deficit hyperactivity disorder (ADHD), on behavioural and brain imaging measures of attention, inhibition and error processing.
Study employs a commonly used ADHD medication (Clonidine) with healthy human adults (only) and examines changes in behaviours that are of relevance to ADHD (inhibition, error processing, selective attention)
Professor Mark Bellgrove26 enrolled1 locationACTRN12615000093583
Completed
Phase 4
The effect of Glycomax 'Trademark' lactoferrin and bovine whey immunoglobulin-rich fraction on gene expression patterns in healthy adults: a double-blind placebo-controlled randomised clinical trial
Immune Function in Healthy Adults
Griffith University120 enrolled1 locationACTRN12614000462684
Recruiting
Phase 4
Rosuvastatin versus Protease Inhibitor Switching for Hypercholesterolaemia in HIV-infected Adults.
Hypercholesterolaemia associated with ritonavir-boosted protease inhibitor therapy in of HIV-infected adults
St. Vincent's Hospital, Sydney60 enrolled1 locationACTRN12612000732886
Completed
Phase 4
The Swinburne Multivitamin Study: The Effects of Multivitamin Supplementation on mood, stress and brain function in older adults
Influence of nutrients on mood and stress in healthy older adultsInvestigate the role of cardiovascular system in relation to mood and stress
Swinburne University100 enrolled1 locationACTRN12612000334808
Active
Phase 4
Aspirin for the prevention of cognitive decline in the Elderly: a Neuro-Vascular Imaging Study (ENVIS-ion), a sub-study of ASPirin in Reducing Events in the Elderly (ASPREE)
Cognitive decline in older adults
Australian National University (ANU)600 enrolled2 locationsACTRN12609000613202