Advanced Hepatocellular Carcinoma (HCC) Clinical Trials

10 recruiting

Advanced Hepatocellular Carcinoma (HCC) Trials at a Glance

10 actively recruiting trials for advanced hepatocellular carcinoma (hcc) are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Phase 2 with 7 trials, with the heaviest enrollment activity in Hangzhou, Shanghai, and Guangzhou. Lead sponsors running advanced hepatocellular carcinoma (hcc) studies include Zhejiang University, Fudan University, and Eastern Hepatobiliary Surgery Hospital.

Browse advanced hepatocellular carcinoma (hcc) trials by phase

Treatments under study

About Advanced Hepatocellular Carcinoma (HCC) Clinical Trials

Looking for clinical trials for Advanced Hepatocellular Carcinoma (HCC)? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Advanced Hepatocellular Carcinoma (HCC) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Advanced Hepatocellular Carcinoma (HCC) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting

Different First-line Immunotherapy for Advancer Hepatocellular Carcinoma: A Prospective Observational Study on Efficacy and Immune Microenvironment

Advanced Hepatocellular Carcinoma (HCC)
Fudan University150 enrolled1 locationNCT07147101
Recruiting
Phase 2

HAI or IV of Adebrelimab, Combined With Bevacizumab and HAI of FOLFOX for Advanced Unresectable Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)
Sun Yat-sen University76 enrolled1 locationNCT06737913
Recruiting
Phase 1Phase 2

Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC

Metastatic Liver CancerAdvanced Hepatocellular Carcinoma (HCC)
Beijing Biotech30 enrolled1 locationNCT07500220
Recruiting
Phase 1

An Open-Label, Phase I Clinical Trial of Super CAR-T With GPC3-Positive Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)GPC3 Positive Hepatocellular Carcinoma
Guangzhou FineImmune Biotechnology Co., LTD.15 enrolled1 locationNCT07493044
Recruiting
Phase 2

Phase 2 Study of WGI-0301 for Advanced HCC

Advanced Hepatocellular Carcinoma (HCC)
Zhejiang Haichang Biotech Co., Ltd.60 enrolled4 locationsNCT06309485
Recruiting
Not Applicable

A Study to Evaluate CG-102-12C in Glypican-3 (GPC3) Positive Advanced Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma (HCC)
Zhejiang University12 enrolled2 locationsNCT07039201
Recruiting
Phase 2

A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion

Advanced Hepatocellular Carcinoma (HCC)
National Cancer Center, Korea128 enrolled2 locationsNCT06828380
Recruiting
Phase 1Phase 2

A Clinical Study of Multi-target Hi-TCR-T Cells in the Treatment of Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)
Eastern Hepatobiliary Surgery Hospital30 enrolled1 locationNCT06902389
Recruiting
Phase 1Phase 2

Autologous Neoantigen-Specific T-Cell Therapy for Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)
Zhejiang University20 enrolled1 locationNCT07123545
Recruiting
Phase 1Phase 2

Personalized Tumor Neoantigen mRNA Therapy for Advanced Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma (HCC)
Zhejiang University30 enrolled1 locationNCT06995105