Metastatic Liver Cancer Clinical Trials

10 recruitingLast updated: June 17, 2026

There are 10 actively recruiting metastatic liver cancer clinical trials across 6 countries. Studies span Phase 1, Phase 2. Top locations include Shanghai, Shanghai Municipality, China, Boston, Massachusetts, United States, Buffalo, New York, United States. Updated daily from ClinicalTrials.gov.


Metastatic Liver Cancer Trials at a Glance

10 actively recruiting trials for metastatic liver cancer are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Phase 1 with 6 trials, with the heaviest enrollment activity in Shanghai, Boston, and Buffalo. Lead sponsors running metastatic liver cancer studies include Eureka Therapeutics Inc., EtiraRx Australia Pty Ltd, and Changhai Hospital.

Browse metastatic liver cancer trials by phase

Treatments under study

About Metastatic Liver Cancer Clinical Trials

Looking for clinical trials for Metastatic Liver Cancer? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Metastatic Liver Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Metastatic Liver Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Phase 1Phase 2

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

Hepatocellular CarcinomaMetastatic Liver CancerLiver Cancer, Adult+1 more
Eureka Therapeutics Inc.60 enrolled8 locationsNCT04864054
Recruiting
Phase 1

A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors

Metastatic Breast CancerAdvanced Solid TumorMetastatic Ovarian Cancer+3 more
EtiraRx Australia Pty Ltd36 enrolled5 locationsNCT06533332
Recruiting
Phase 2

68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)

Liver CancerHepatocellular CarcinomaMetastatic Liver Cancer
Melissa Lumish10 enrolled1 locationNCT06852820
Recruiting
Phase 1Phase 2

Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC

Metastatic Liver CancerAdvanced Hepatocellular Carcinoma (HCC)
Beijing Biotech30 enrolled1 locationNCT07500220
Recruiting

Streamlining Radioembolization for CCC and Metastatic Liver Cancer

CholangiocarcinomaMetastatic Liver CancerMetastatic Colorectal Carcinoma (mCRC)
Seoul National University Hospital60 enrolled4 locationsNCT07043387
Recruiting
Phase 1Phase 2

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

Liver CancerMetastatic Liver CancerLiver Neoplasms+3 more
Eureka Therapeutics Inc.15 enrolled2 locationsNCT04634357
Recruiting
Phase 1

Mts105 for Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma (HCC)HCC - Hepatocellular CarcinomaLiver Cancer, Adult+1 more
Shen Lin14 enrolled1 locationNCT06689540
Recruiting

Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases

Colorectal, CancerLiver MetastasesMetastatic Liver Cancer
Hospital Universitario La Fe30 enrolled1 locationNCT04616495
Recruiting

PDO/PDO-TIL/PDOTS for Drug Screen

Liver CancerMetastatic Liver Cancer
Shanghai Zhongshan Hospital30 enrolled1 locationNCT05913141
Recruiting
Phase 1

Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases

Colorectal, CancerMetastatic Liver Cancer
Changhai Hospital18 enrolled1 locationNCT05240950