Phase 1 Advanced Solid Cancer Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1Phase 2
A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
Advanced Solid Cancers
BioNTech SE245 enrolled8 locationsNCT07186842
Recruiting
Phase 1Phase 2
A Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D Mutation
Advanced Solid CancerKRAS G12D Mutation
Arvinas Inc.159 enrolled14 locationsNCT07023731
Recruiting
Phase 1
ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers
Metastatic Solid TumorsAdvanced Solid CancersAdvanced Malignancy
Adcytherix SAS290 enrolled4 locationsNCT07238075
Recruiting
Phase 1
A Phase I Study of SIM0609 in Adult Participants With Locally Advanced/Metastatic Solid Tumors
Advanced Solid Cancer
Jiangsu Simcere Pharmaceutical Co., Ltd.232 enrolled6 locationsNCT07265921
Recruiting
Phase 1
A Phase 1 Study of APX-343A as Monotherapy or in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Advanced Solid CancerAdvanced Solid Tumor (Phase 1)
Aptabio Therapeutics, Inc.110 enrolled3 locationsNCT07123415
Recruiting
Phase 1Phase 2
A Study of MHB046C Injection in Patients With Advanced Solid Tumors
Advanced Solid Cancer
Minghui Pharmaceutical (Hangzhou) Ltd200 enrolled1 locationNCT06985355
Recruiting
Phase 1
Study of SC-102 in Patients With Advanced Solid Tumors
Advanced Solid Cancers
Tianjin ConjuStar Biologics Co., Ltd.120 enrolled1 locationNCT06710158
Recruiting
Phase 1
A Phase Ia/ Ib Study of HS387 in Subjects With Advanced Solid Tumors
Advanced Solid Cancers
Zhejiang Hisun Pharmaceutical Co. Ltd.110 enrolled1 locationNCT07092748
Recruiting
Phase 1
Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors
Breast CancerOvarian CancerProstate Cancer+4 more
Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd30 enrolled2 locationsNCT06666270
Recruiting
Phase 1
APG-2449 in Patients With Advanced Solid Tumors
Advanced Solid Cancer
Ascentage Pharma Group Inc.165 enrolled9 locationsNCT03917043
Completed
Phase 1
A phase 1 clinical trial of BIL06v/Alhydrogel to evaluate the safety, tolerability, immunogenicity and anti-tumour activity and to determine the most effective dose of BIL06v/Alhydrogel to treat patients with advanced forms of solid cancers
Advanced Solid Cancers
Biosceptre (Aust) Pty Limited30 enrolled2 locationsACTRN12618000838213