AF Clinical Trials

1,049 recruitingLast updated: June 18, 2026

There are 1,049 actively recruiting af clinical trials across 86 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


AF Trials at a Glance

1,049 actively recruiting trials for af are listed on ClinicalTrialsFinder across 6 cities in 86 countries. The largest study group is Not Applicable with 424 trials, with the heaviest enrollment activity in Boston, New York, and Beijing. Lead sponsors running af studies include Beijing Anzhen Hospital, University of California, San Francisco, and Cairo University.

Treatments under study

About AF Clinical Trials

Looking for clinical trials for AF? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new AF trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about AF clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,049 trials

Recruiting
Phase 1Phase 2

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Colorectal, CancerColorectal CarcinomaNon-small Cell Lung Cancer+29 more
Institut de Recherches Internationales Servier554 enrolled27 locationsNCT05786924
Recruiting
Phase 2

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Atrial Fibrillation (AF)
Regeneron Pharmaceuticals1,200 enrolled48 locationsNCT07175428
Recruiting

Special Drug Use-results Surveillance of Tafinlar/Mekinist

BRAF V600E Mutation-positive Unresectable Advanced or Recurrent Solid Tumor
Novartis Pharmaceuticals110 enrolled70 locationsNCT06262919
Recruiting
Not Applicable

Unipolar Voltage Mapping for Personalized Atrial Fibrillation Ablation

Atrial Fibrillation (AF)
China National Center for Cardiovascular Diseases200 enrolled1 locationNCT07630857
Recruiting
Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled22 locationsNCT07105111
Recruiting
Not Applicable

Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation

Sleep-disordered breathing (SDB)Obstructive Sleep ApneaArrhythmia+3 more
Beijing Anzhen Hospital658 enrolled27 locationsNCT07444372
Recruiting
Phase 2

Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate

SchizophreniaSchizo Affective DisorderSymptom, Cognitive
National Cheng-Kung University Hospital90 enrolled1 locationNCT06340789
Recruiting

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

Chronic Graft vs. Host Disease
National Cancer Institute (NCI)650 enrolled1 locationNCT00092235
Recruiting

Radiographic Cortical Thickness of the Humerus in Detecting Post-Stroke Regional Bone Loss

Dual-energy x-ray absorptiometryOsteoporosisHemiparesis After Stroke
Istanbul Physical Medicine Rehabilitation Training and Research Hospital65 enrolled1 locationNCT07651306
Recruiting
Not Applicable

Evaluation of Post-operative Pain After Stabilization of Free Gingival Graft for Keratinized Tissue Augmentation Around Natural Teeth Using Titanium Tacks Versus Standard Suturing Technique.

To Clinically Compare Post-operative Pain Between Free Gingival Grafts Stabilization Around Natural Teeth Using Titanium Tacks vs Suturing Technique
Karim Abdelrahim Mohamed Abdelsamad24 enrolled1 locationNCT07655349
Recruiting

Cleaner Long-tErm Assessment Registry - Venous Insights and Efficacy With eXtended Tracking

Deep Vein Thrombosis (DVT)Venous EmbolismThrombus in the Peripheral Venous Vasculature+1 more
Argon Medical Devices185 enrolled4 locationsNCT07102160
Recruiting
Phase 2

Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco96 enrolled7 locationsNCT07110246
Recruiting

Prediction Model for MINS After Major Hepatobiliary Surgery

Postoperative ComplicationsLiver NeoplasmMyocardial Injury After Noncardiac Surgery (MINS)+1 more
Beijing Tsinghua Chang Gung Hospital1,800 enrolled6 locationsNCT07335042
Recruiting
Not Applicable

Screening in Primary Care of Advanced Liver Fibrosis in NAFLD and/or Alcoholic Patients

Liver FibrosisNon-alcoholic Fatty Liver Disease NAFLDAlcoholic Liver Disease (ALD)
University Hospital, Angers1,788 enrolled13 locationsNCT05699018
Recruiting

Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation

Atrial Fibrillation (AF)
University of Edinburgh300 enrolled1 locationNCT06951100
Recruiting

Left Atrial and Left Ventricular Structural and Functional Evaluation by CCTA for Predicting Post-Ablation Outcomes in Patients With Atrial Fibrillation

Atrial Fibrillation (AF)
Nanjing First Hospital, Nanjing Medical University600 enrolled1 locationNCT07651046
Recruiting
Not Applicable

EFFECT OF NITI SYSTEMS AND XP-ENDO FINISHER ON POSTOPERATIVE PAIN

Postoperative Pain After Endodontic Treatment
BUSRA OZTURK80 enrolled2 locationsNCT07642596
Recruiting
Not Applicable

Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

Paroxysmal AF
Medtronic Cardiac Ablation Solutions300 enrolled22 locationsNCT07308847
Recruiting
Phase 2

Clinical Phase 2 Trial of AP31969 Versus Placebo for Rhythm Control of Atrial Fibrillation

Atrial Fibrillation (AF)
Acesion Pharma200 enrolled44 locationsNCT07267949
Recruiting
Not Applicable

Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients

Feasibility, Tolerance and Safety of VR Delivery in an Adult ICU
Milton S. Hershey Medical Center30 enrolled1 locationNCT07649876