Early Phase 1 AF Clinical Trials

11 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 111 of 11 trials

Recruiting
Early Phase 1

A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Glioma

BRAF V600E Mutation
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins24 enrolled1 locationNCT06610682
Recruiting
Early Phase 1

Human Amniotic-Derived Mesenchymal Stem Cell Therapy for Calciphylaxis

EfficacyTreatmentChronic Kidney Diseases+3 more
The First Affiliated Hospital with Nanjing Medical University9 enrolled1 locationNCT04592640
Recruiting
Early Phase 1

Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma

Melanoma Stage IVBRAF V600 MutationMelanoma Stage III
H. Lee Moffitt Cancer Center and Research Institute50 enrolled1 locationNCT04741997
Recruiting
Early Phase 1

Prevention of Graft Rejection in Hematopoietic Stem Cell Transplant (HSCT) Recipients

Hematopoietic Stem Cell TransplantationGraft Failure
Children's Hospital Medical Center, Cincinnati20 enrolled1 locationNCT07244419
Recruiting
Early Phase 1

Efficacy and Safety Study of DC-CIK Cell Therapy Combined With Epaloliposide, Vortexil, and Regorafenib as Third-line Treatment for Advanced Colorectal Cancer.

DC-CIK TreatmentRegorafenib
JIANG LONGWEI14 enrolled1 locationNCT07343791
Recruiting
Early Phase 1

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

Endometrial CancerNear Infrared Fluorescence ImagingCYTALUX (Pafolacianine) Injection+1 more
Abramson Cancer Center at Penn Medicine10 enrolled2 locationsNCT07278986
Recruiting
Early Phase 1

Tolerance Through Mixed Chimerism (Sip-Tego)

Kidney FailureTransplant Recipient (Kidney)Immunosuppresion+2 more
Tatsuo Kawai, MD, PhD12 enrolled1 locationNCT06972069
Recruiting
Early Phase 1

Thiamine Intervention and Coronary Artery Bypass Grafting

Coronary Heart DiseaseCoronary Artery Bypass Grafting
University of California, Los Angeles52 enrolled1 locationNCT06326996
Recruiting
Early Phase 1

Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients

Safety IssuesTolerance
Kariya Pharmaceuticals88 enrolled1 locationNCT06189170
Recruiting
Early Phase 1

Study on B7-H3 Targeted Affibody Radioligand Probes for PET Imaging of Solid Tumors

B7H3CD276 AffibodyPET/CT Imaing
Peking University Cancer Hospital & Institute50 enrolled1 locationNCT06454955
Completed
Early Phase 1

The assessment of changes of respiratory parameters and bioelectrical activity of accessory respiratory muscles depending on applied breathing stimulation in patients after ischemic stroke

Patients after ischemic stroke
Wroclaw Medical University60 enrolled1 locationACTRN12613001315707