Phase 1 AF Clinical Trials
85 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 85 trials
Recruiting
Phase 1
A First in Human Study of the Safety, Tolerability, and the Physiologically Based Pharmacokinetics of XFB19 in Healthy Adult Volunteers.
Focus of the Study: Safety of XFB19
Xfibra, Inc.40 enrolled1 locationNCT05361733
Recruiting
Phase 1Phase 2
Anthocyanin-Rich Table Grape Powder for Prophylaxis of Post-Operative Atrial Fibrillation
Post-operative Atrial Fibrillation (POAF)
University of Michigan70 enrolled1 locationNCT05991700
Recruiting
Phase 1Phase 2
Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation
Ischemia Reperfusion InjuryDelayed Graft Function
Rhode Island Hospital20 enrolled1 locationNCT04005469
Recruiting
Phase 1
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors
Metastatic Hepatocellular CarcinomaLocal Advanced Hepatocellular CarcinomaAlpha-fetoprotein (AFP)-Producing Gastric Cancer+2 more
BeOne Medicines140 enrolled20 locationsNCT06427941
Recruiting
Phase 1Phase 2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Non-small Cell Lung CancerMetastatic Lung CancerMetastatic Lung Non-Small Cell Carcinoma+18 more
Institut de Recherches Internationales Servier554 enrolled11 locationsNCT05786924
Recruiting
Phase 1
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
OncologyMEK MutationRAF Gene Mutation
Nested Therapeutics, Inc230 enrolled23 locationsNCT06326411
Recruiting
Phase 1
Bicalutamide Therapy in Young Women With NAFLD and PCOS
PCOSNAFLD
University of California, San Francisco50 enrolled1 locationNCT05979389
Recruiting
Phase 1
A Clinical Study of GenSci134 in Healthy Adults and Adult Growth Hormone Deficiency(AGHD)
SafetyTolerabilityAdult Growth Hormone Deficiency
Changchun GeneScience Pharmaceutical Co., Ltd.64 enrolled1 locationNCT07016802
Recruiting
Phase 1Phase 2
Acetazolamide for Treatment Resistant Schizophrenia
SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD60 enrolled2 locationsNCT04887792
Recruiting
Phase 1
Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer
Thyroid Gland Anaplastic CarcinomaBRAF NP_004324.2:p.V600EBRAF V600K Mutation Present
City of Hope Medical Center6 enrolled3 locationsNCT03975231
Recruiting
Phase 1Phase 2
Ocrelizumab for Psychosis by Autoimmunity
SchizophreniaSchizo-Affective Type of Psychosis
The Methodist Hospital Research Institute40 enrolled1 locationNCT03971487
Recruiting
Phase 1
Clinical Study of EBV-TCR-T Cells for EBV Infection After Allogenic HSCT
EBV Infection After Allogenic HSCT
Chinese PLA General Hospital12 enrolled1 locationNCT06119256
Recruiting
Phase 1Phase 2
Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Graft vs Host Disease
National Cancer Institute (NCI)50 enrolled2 locationsNCT05531786
Recruiting
Phase 1Phase 2
A Study of REGN7041 for Active Noninfectious Uveitis in Adult Participants
Active Noninfectious Uveitis Affecting the Posterior Segment
Regeneron Pharmaceuticals72 enrolled4 locationsNCT07218770
Recruiting
Phase 1
Pharmacokinetics of Sulopenem Etzadroxil Plus Probenecid in Adolescents
Pharmacokinetics After Oral Intake
Iterum Therapeutics, International Limited12 enrolled1 locationNCT07092813
Recruiting
Phase 1Phase 2
Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia
SchizophreniaSchizo Affective Disorder
Vishwajit Nimgaonkar, MD PhD160 enrolled1 locationNCT03794076
Recruiting
Phase 1
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
SafetyDemoralization
Gustavo Vazquez15 enrolled1 locationNCT06818994
Recruiting
Phase 1Phase 2
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16)
Primary Peritoneal CarcinomaFallopian Tube CarcinomaEpithelial Ovarian Cancer+1 more
Beijing Biotech36 enrolled1 locationNCT07480954
Recruiting
Phase 1Phase 2
Immune Tolerance Induction After Liver Transplantation
Liver TransplantationEnd Stage Liver DiseaseImmune Tolerance+6 more
University of California, Los Angeles12 enrolled1 locationNCT07269041
Recruiting
Phase 1
Fecal Microbiota Transplant and Dietary Fiber Supplementation for the Treatment of Gut Graft Versus Host Disease
Intestinal Graft Versus Host Disease
Fred Hutchinson Cancer Center72 enrolled1 locationNCT05067595