Alport Syndrome Clinical Trials

9 recruiting

Alport Syndrome Trials at a Glance

9 actively recruiting trials for alport syndrome are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Phase 2 with 2 trials, with the heaviest enrollment activity in Barcelona, Chapel Hill, and Ann Arbor. Lead sponsors running alport syndrome studies include Bayer, Institut National de la Santé Et de la Recherche Médicale, France, and Alport Syndrome Foundation.

Browse alport syndrome trials by phase

Treatments under study

About Alport Syndrome Clinical Trials

Looking for clinical trials for Alport Syndrome? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Alport Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Alport Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting

ASF Alport Patient Registry

Alport SyndromeThin Basement Membrane DiseaseHereditary Nephritis
Alport Syndrome Foundation2,500 enrolled1 locationNCT06526741
Recruiting
Phase 2

BAY3401016; Biomarker Study Alport

Alport Syndrome
Bayer60 enrolled60 locationsNCT07211685
Recruiting
Not Applicable

NEPTUNE Match Study

Nephrotic Syndrome in ChildrenAlport SyndromeFocal Segmental Glomerulosclerosis+6 more
University of Michigan375 enrolled16 locationsNCT04571658
Recruiting
Phase 2

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

Alport SyndromeFocal Segmental GlomerulosclerosisImmunoglobulin A Nephropathy+2 more
Travere Therapeutics, Inc.67 enrolled47 locationsNCT05003986
Recruiting

Eurbio-Alport (RaDiCo Cohort) (RaDiCo Eurbio-Alport)

Alport Syndrome
Institut National de la Santé Et de la Recherche Médicale, France700 enrolled1 locationNCT05927467
Recruiting

Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

Alport SyndromePediatric Kidney DiseaseThin Basement Membrane Disease+2 more
University Hospital Goettingen800 enrolled1 locationNCT02378805
Recruiting
Phase 4

Albuminuria Lowering Effect of Dapagliflozin, Spironolactone and Their Combination in Adult Patients with Alport Syndrome (COMBINE-ALPORT)

Alport SyndromeThin Basement Membrane DiseaseAlport Nephropathy
Stefan Lujinschi34 enrolled1 locationNCT06499948
Recruiting

National Registry of Rare Kidney Diseases

Denys-Drash SyndromeTuberous SclerosisAutosomal Recessive Polycystic Kidney Disease+81 more
UK Kidney Association35,000 enrolled1 locationNCT06065852
Recruiting

Genotype-Phenotype Correlations in Patients With Alport Syndrome

Alport Syndrome
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine8,165 enrolled1 locationNCT04947813