Nephrotic Syndrome in Children Clinical Trials

13 recruitingLast updated: May 21, 2026

There are 13 actively recruiting nephrotic syndrome in children clinical trials across 5 countries. Studies span Phase 3, Not Applicable, Phase 2, Phase 4. Top locations include Hangzhou, Zhejiang, China, Philadelphia, Pennsylvania, United States, New Hyde Park, New York, United States. Updated daily from ClinicalTrials.gov.


Nephrotic Syndrome in Children Trials at a Glance

13 actively recruiting trials for nephrotic syndrome in children are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Phase 3 with 4 trials, with the heaviest enrollment activity in Hangzhou, Philadelphia, and New Hyde Park. Lead sponsors running nephrotic syndrome in children studies include Mao Jianhua, Northwell Health, and The Children's Hospital of Zhejiang University School of Medicine.

Browse nephrotic syndrome in children trials by phase

About Nephrotic Syndrome in Children Clinical Trials

Looking for clinical trials for Nephrotic Syndrome in Children? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Nephrotic Syndrome in Children trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Nephrotic Syndrome in Children clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Not Applicable

NEPTUNE Match Study

Nephrotic Syndrome in ChildrenAlport SyndromeFocal Segmental Glomerulosclerosis+6 more
University of Michigan375 enrolled16 locationsNCT04571658
Recruiting
Not Applicable

A Pilot Trial of taVNS for SRNS in Children (kidNEY-VNS)

Nephrotic Syndrome in ChildrenFocal Segmental GlomerulosclerosisMinimal Change Disease
Northwell Health10 enrolled2 locationsNCT05583942
Recruiting
Not Applicable

taVNS for FRNS in Children

Nephrotic Syndrome in ChildrenFocal Segmental GlomerulosclerosisMinimal Change Disease
Northwell Health30 enrolled2 locationsNCT05588063
Recruiting
Phase 2

A Study of Anti-CD38 Monoclonal Antibody (SG301) Subcutaneous Injection in Children With Nephrotic Syndrome With Frequent Relapses or Steroid Dependence

Nephrotic Syndrome in Children
Mao Jianhua30 enrolled1 locationNCT07087314
Recruiting

Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.

EdemaNephrotic Syndrome in ChildrenMembranous Nephropathy+10 more
University of Michigan150 enrolled1 locationNCT05505500
Recruiting
Phase 2

Dupilumab Therapy in Nephrotic Syndrome in Children

Nephrotic Syndrome in ChildrenNephrotic Syndrome Steroid-Dependent
National University Hospital, Singapore66 enrolled2 locationsNCT07091175
Recruiting
Phase 3

REduced-dose Steroid PrOtocol for Childhood Nephrotic SyndromE (RESPONSE)

Nephrotic Syndrome in ChildrenNephrotic SyndromeNephrotic Syndrome, Minimal Change+1 more
The Hospital for Sick Children50 enrolled1 locationNCT06635720
Recruiting
Phase 3

Study of the Telitacicept in Pediatric Patients With Frequently Relapsing or Steroid Dependent Nephrotic Syndrome

Nephrotic Syndrome in ChildrenTelitacicept
The Children's Hospital of Zhejiang University School of Medicine20 enrolled1 locationNCT06125405
Recruiting
Phase 4

The Efficacy and Safety of Prednisone Combined With Huaiqihuang Granule for Primary Nephrotic Syndrome in Children

Nephrotic Syndrome in Children
Jianhua Zhou402 enrolled26 locationsNCT05772871
Recruiting
Phase 4

Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years

Nephrotic Syndrome in Children
Mansoura University60 enrolled1 locationNCT06417320
Recruiting
Phase 2

Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil in Children With Steroid-dependent Nephrotic Syndrome

Nephrotic Syndrome in Children
Children's Hospital of Chongqing Medical University46 enrolled1 locationNCT05843968
Recruiting
Phase 3

Study of Adrenocorticotropic Hormone on Children With Frequent Relapse or Steroid-dependent Nephrotic Syndrome: a Prospective, Multicenter, Randomized,Open-label Clinical Trial.

Nephrotic Syndrome in Children
Mao Jianhua140 enrolled8 locationsNCT06079788
Recruiting
Phase 3

Study of Rituximab Monotherapy on Children With New-onset Nephrotic Syndrome: A Randomized Controlled Trial

Nephrotic Syndrome in ChildrenRituximab
The Children's Hospital of Zhejiang University School of Medicine80 enrolled1 locationNCT05734794