Phase 1 Amyotrophic Lateral Sclerosis(ALS) Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1Phase 2
A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis.
Amyotrophic Lateral Sclerosis(ALS)
Nura Bio80 enrolled6 locationsNCT07369076
Recruiting
Phase 1Phase 2
Intestinal Microbiome Transplant in ALS
Amyotrophic Lateral Sclerosis(ALS)
Duke University20 enrolled1 locationNCT07017946
Recruiting
Phase 1Phase 2
First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)
Amyotrophic Lateral Sclerosis(ALS)Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Regeneron Pharmaceuticals42 enrolled16 locationsNCT06351592
Recruiting
Phase 1
The Safety, Tolerability and Preliminary Efficacy of Derived Motor Neuron Progenitor Cells (XS228CN) in Subjects With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis(ALS)
XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.12 enrolled1 locationNCT07118319
Recruiting
Phase 1
Clinical Study of Regulatory T Cells (Tregs) in the Treatment of Neurodegenerative Diseases
Amyotrophic Lateral Sclerosis(ALS)
Novabio Therapeutics12 enrolled1 locationNCT06671236
Recruiting
Phase 1Phase 2
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Amyotrophic Lateral Sclerosis(ALS)Alzheimer Disease (AD)Parkinson Disease (PD)+1 more
Ashvattha Therapeutics, Inc.65 enrolled3 locationsNCT05395624
Recruiting
Phase 1
A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418
Amyotrophic Lateral Sclerosis(ALS)Parkinson Disease Psychosis
1ST Biotherapeutics, Inc.64 enrolled1 locationNCT05995782