Phase 2 Amyotrophic Lateral Sclerosis Clinical Trials
18 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–18 of 18 trials
Recruiting
Phase 1Phase 2
Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS
Amyotrophic Lateral Sclerosis
Vector Y Therapeutics12 enrolled11 locationsNCT07287397
Recruiting
Phase 2Phase 3
HEALEY ALS Platform Trial - Master Protocol
Amyotrophic Lateral Sclerosis
Merit E. Cudkowicz, MD1,500 enrolled78 locationsNCT04297683
Recruiting
Phase 2
Dazucorilant in Patients With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Corcept Therapeutics279 enrolled35 locationsNCT05407324
Recruiting
Phase 1Phase 2
Evaluation of the Combined Therapy of EH-301 and N-acetylcysteine Together With Riluzole in Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis
Biogipuzkoa Health Research Institute90 enrolled1 locationNCT07414212
Recruiting
Phase 2
Tofersen in Non-SOD1 ALS
ALS (Amyotrophic Lateral Sclerosis)
Washington University School of Medicine30 enrolled1 locationNCT07294144
Recruiting
Phase 2
A Study of Ranolazine in ALS
Amyotrophic Lateral Sclerosis
Swathy Chandrashekhar, MBBS72 enrolled7 locationsNCT06527222
Recruiting
Phase 2Phase 3
Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS
Amyotrophic Lateral Sclerosis
Mario Negri Institute for Pharmacological Research246 enrolled19 locationsNCT06126315
Recruiting
Phase 2
A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS
Amyotrophic Lateral Sclerosis
Oliver Blanchard30 enrolled2 locationsNCT06249867
Recruiting
Phase 2Phase 3
RAPA-501 Therapy for ALS
Amyotrophic Lateral Sclerosis
Rapa Therapeutics LLC41 enrolled1 locationNCT04220190
Recruiting
Phase 1Phase 2
TP04HN106 in the Treatment of Patients With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Talengen Institute of Life Sciences, Shenzhen, P.R. China.60 enrolled1 locationNCT06726577
Recruiting
Phase 1Phase 2
Exploring Nasal Drop Therapy With Small Extracellular Vesicles for ALS
Amyotrophic Lateral Sclerosis
Xuanwu Hospital, Beijing38 enrolled1 locationNCT06598202
Recruiting
Phase 2
An Open Label Extension of the double-blind randomised, placebo-controlled clinical trial to test the treatment of amyotrophic lateral sclerosis with ambroxol.
Amyotrophic Lateral Sclerosis
The Florey Institute of Neuroscience and Mental Health (part of the University of Melbourne)20 enrolled5 locationsACTRN12624001204538
Recruiting
Phase 2
Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis (STEMALS)
Amyotrophic Lateral Sclerosis
Casa Sollievo della Sofferenza IRCCS30 enrolled4 locationsNCT06344260
Recruiting
Phase 2
A double-blind randomised, placebo-controlled clinical trial to test the treatment of amyotrophic lateral sclerosis with ambroxol.
Amyotrophic Lateral Sclerosis
The Florey Institute of Neuroscience and Mental Health (part of the University of Melbourne)50 enrolled5 locationsACTRN12622001380785
Completed
Phase 2
3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral SclerosisMotor Neuron Disease
Macquarie University16 enrolled1 locationACTRN12621000864820
Completed
Phase 2
Safety and tolerability of Trimetazidine in amyotrophic lateral sclerosis (ALS)
Amyotrophic Lateral Sclerosis
The University of Queensland36 enrolled3 locationsACTRN12620000945921
Not Yet Recruiting
Phase 2
Study to Assess the Efficacy and Safety of Tecfidera in Patients with Amyotrophic Lateral Sclerosis - TEALS Study
Amyotrophic Lateral Sclerosis
University of Sydney90 enrolled6 locationsACTRN12618000534280
Recruiting
Phase 2
Narrow band ultraviolet B (UVB) phototherapy in amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis
Western Sydney Local Health District20 enrolled1 locationACTRN12615000802505