Phase 2 ART Clinical Trials

434 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 434 trials

Recruiting
Phase 2

Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial

Metastatic Alveolar Soft Part SarcomaAdvanced Soft Tissue SarcomaAdvanced Alveolar Soft Part Sarcoma+2 more
National Cancer Institute (NCI)27 enrolled13 locationsNCT05333458
Recruiting
Phase 2

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Breast CancerColorectal, CancerLung Cancer+13 more
Brigham and Women's Hospital134 enrolled2 locationsNCT04899908
Recruiting
Phase 2

Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis

Primary Knee Osteoarthritis
Enlivex Therapeutics Ltd.270 enrolled17 locationsNCT07580716
Recruiting
Phase 1Phase 2

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

NeutropeniaInfectionsWarts+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT00967785
Recruiting
Phase 2

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
AbbVie180 enrolled97 locationsNCT06972446
Recruiting
Phase 2

Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

Psoriatic Arthritis
Merck Sharp & Dohme LLC140 enrolled43 locationsNCT07486960
Recruiting
Phase 2

A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)

Radiographic Axial Spondyloarthritis
Merck Sharp & Dohme LLC315 enrolled100 locationsNCT07133633
Recruiting
Phase 1Phase 2

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

CAR-T CellSLESystemic Lupus Erythematosus (SLE)+4 more
Children's Hospital of Philadelphia24 enrolled1 locationNCT06839976
Recruiting
Phase 2

Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage.

Patellofemoral osteoarthritis
University Hospital, Basel, Switzerland75 enrolled9 locationsNCT06163573
Recruiting
Phase 2

Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

Pain, PostoperativeOsteoarthritis Thumb
Stanford University121 enrolled2 locationsNCT04676802
Recruiting
Phase 2

Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABG

Ischemic Heart Disease
Rohto Pharmaceutical Co., Ltd.50 enrolled1 locationNCT07192211
Recruiting
Phase 2

Spironolactone for Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension
National Institutes of Health Clinical Center (CC)70 enrolled1 locationNCT01712620
Recruiting
Phase 2Phase 3

Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis

Knee arthritis
NYU Langone Health100 enrolled1 locationNCT05020028
Recruiting
Phase 2

Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell Arteritis

Giant Cell Arteritis (GCA)
National Institute of Allergy and Infectious Diseases (NIAID)78 enrolled7 locationsNCT07108387
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis

Arthritis, Psoriatic
Janssen Research & Development, LLC240 enrolled68 locationsNCT07321873
Recruiting
Phase 2

Transition to KPL-387 Monotherapy Dosing & Administration Study

PericarditisHeart DiseasesRecurrent Pericarditis
Kiniksa Pharmaceuticals International, plc80 enrolled32 locationsNCT07288216
Recruiting
Phase 2

Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers

Healthy Participants With Lower-than-average Mental Well-being
Robin Carhart-Harris, PhD, MA120 enrolled1 locationNCT06626139
Recruiting
Phase 1Phase 2

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

Rheumatoid ArthritisIdiopathic Inflammatory MyopathiesSystemic Sclerosis+1 more
Nkarta, Inc.240 enrolled17 locationsNCT06733935
Recruiting
Phase 2

Desloratadine as Adjunct Therapy for Rheumatoid Arthritis

Rheumatoid ArthritisRheumatoid Arthritis (RA)
Horus University60 enrolled1 locationNCT07632872
Recruiting
Phase 2

Effect of Roflumilast as Add-On Therapy in Rheumatoid Arthritis

Rheumatoid ArthritisRheumatoid Arthritis (RA)
Horus University50 enrolled1 locationNCT07632846