Phase 2 Autoimmune Clinical Trials
40 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 40 trials
Recruiting
Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
Autoimmune DiseaseProteinuriaGlomerular Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled2 locationsNCT00977977
Recruiting
Phase 2
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)354 enrolled2 locationsNCT02579967
Recruiting
Phase 1Phase 2
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Rheumatoid Arthritis (RA)Autoimmune Rheumatologic DiseaseDiffuse Cutaneous Systemic Sclerosis+1 more
Quell Therapeutics Limited16 enrolled6 locationsNCT07473154
Recruiting
Phase 2
A Study in Participants With Anti-NMDAR Encephalitis and Anti-NMDAR Autoantibody-Associated Psychiatric Disease
Autoimmune EncephalitisAnti-N-methyl-D-aspartate Receptor (NMDAR) Encephalitis (ANRE)Anti-N-methyl-D-aspartate Receptor (NMDAR) Antibody-associated Psychiatric Disease
Arialys Australia Pty Ltd30 enrolled1 locationNCT07093333
Recruiting
Phase 2
Is [18F]-DPA-714 PET a Good Marker of Neuroinflammation in Autoimmune Encephalitis?
Autoimmune Encephalitis (AE)
University Hospital, Toulouse40 enrolled1 locationNCT07488117
Recruiting
Phase 2
Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients
Autoimmune Lymphoproliferative Syndrome
National Institute of Allergy and Infectious Diseases (NIAID)15 enrolled3 locationsNCT06730126
Recruiting
Phase 2
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity
Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)66 enrolled1 locationNCT04339777
Recruiting
Phase 1Phase 2
Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Autoimmune Diseases
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT06435897
Recruiting
Phase 2
Belimumab in Autoimmune Hepatitis
Autoimmune Hepatitis
University Health Network, Toronto48 enrolled5 locationsNCT06381453
Recruiting
Phase 2
Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease
Meniere's DiseaseAutoimmune Inner Ear Disease
Northwell Health57 enrolled1 locationNCT03587701
Recruiting
Phase 1Phase 2
Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders
Systemic Lupus ErythematosusLupusAutoimmune Disorders+2 more
M.D. Anderson Cancer Center47 enrolled2 locationsNCT06434363
Recruiting
Phase 2
Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab
Warm Autoimmune Hemolytic AnemiaPrimary immune thrombocytopenia
Novartis Pharmaceuticals60 enrolled14 locationsNCT07039422
Recruiting
Phase 2
Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy
Autoimmune Disorders
National Institute of Allergy and Infectious Diseases (NIAID)30 enrolled8 locationsNCT07103746
Recruiting
Phase 2
A Study to Evaluate CM336 in Adults With Autoimmune Bullous Disease
Autoimmune Bullous Disease
Shandong First Medical University30 enrolled1 locationNCT06900010
Recruiting
Phase 1Phase 2
Daratumumab in Primary Antiphospholipid Syndrome
Autoimmune Disorders
National Institute of Allergy and Infectious Diseases (NIAID)22 enrolled8 locationsNCT05671757
Recruiting
Phase 1Phase 2
Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases
Autoimmune Diseases
Beijing GoBroad Hospital18 enrolled1 locationNCT06688799
Recruiting
Phase 2
Study to Evaluate the Safety and Feasibility of Diamyd® in Individuals at Risk for Type 1 Diabetes
PreventionDiabetes Mellitus, Type 1Autoimmune Diseases
Diamyd Medical AB16 enrolled1 locationNCT05683990
Recruiting
Phase 2
Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals
Hematopoietic and Lymphatic System NeoplasmAutoimmune DiseaseRespiratory Syncytial Virus Infection
Fred Hutchinson Cancer Center60 enrolled3 locationsNCT06817889
Recruiting
Phase 1Phase 2
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 1Phase 2
Clinical Application of Al18F-NOTA-FAPI-04 PET/CT or PET/MRI Imaging in Malignant Tumor,Cardiovascular or Immune Disease
Malignant TumorHyperthyroidism, AutoimmuneCardiovascular Abnormalities
Peking Union Medical College Hospital600 enrolled1 locationNCT07400224