Phase 1 Bipolar Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1Phase 2
Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine
SchizophreniaMajor Depressive DisorderBipolar I Disorder
Mapi Pharma Ltd.24 enrolled6 locationsNCT07185815
Recruiting
Phase 1Phase 2
A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder
Bipolar I Disorder
Alzamend Neuro, Inc.20 enrolled1 locationNCT07540338
Recruiting
Phase 1Phase 2
Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian
Bipolar Disorder (BD)
Babes-Bolyai University50 enrolled1 locationNCT07399626
Recruiting
Phase 1
Adjunctive Allogeneic Mesenchymal Stem Cells for Treatment-resistant Bipolar Depression
Treatment-resistant Bipolar Depression
The University of Texas Health Science Center, Houston30 enrolled1 locationNCT03522545
Recruiting
Phase 1Phase 2
Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression
Bipolar Depression
Laureate Institute for Brain Research, Inc.20 enrolled1 locationNCT06088732
Recruiting
Phase 1
Alexithymia Intervention for Suicide
SchizophreniaPost Traumatic Stress DisorderSuicide+2 more
VA Office of Research and Development40 enrolled1 locationNCT05724953
Recruiting
Phase 1
Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression
Bipolar Depression
University Health Network, Toronto30 enrolled1 locationNCT06506019
Completed
Phase 1
A placebo and comparator controlled phase 1, safety and tolerability study of 3 ascending doses of INP105 (intranasal OLZ by I231 POD® device).
Acute Agitation in SchizophreniaAcute Agitation in Bipolar I Disorder
Clinical Network Services (CNS) Pty Ltd36 enrolled1 locationACTRN12618000966291
Not Yet Recruiting
Phase 1
Effects of lithium and fampridine on electroencephalography profiles in healthy volunteers
Bipolar Disorder
University of Otago24 enrolled1 locationACTRN12617001339347
Completed
Phase 1
Open-Label Study in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of Switching from Oral Risperidone to Risperidone Implant (DLP-114)
SchizophreniaBipolar Disorder IAutistic Disorder
Delpor Australia Pty Ltd17 enrolled1 locationACTRN12617001251314