RecruitingPhase 1NCT05724953

Alexithymia Intervention for Suicide

Alexithymia Intervention for Suicide (ALEXIS)


Sponsor

VA Office of Research and Development

Enrollment

40 participants

Start Date

Oct 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Suicide rates among Veterans with Serious Mental Illness (SMI) are intractably high, representing a serious public health concern and a critical target for interventions. Yet, at present available treatments offer modest benefits. Thus, there remains an urgent need to identify novel approaches to address suicide risk in this population. Previous reports have linked suicide risk with poor social functioning. Emerging evidence from basic affective neuroscience research has indicated that effective social functioning is contingent on intact emotion awareness. Consistent with these findings, individuals with SMI at risk of suicide display social functioning difficulties along with poor emotion awareness (i.e., alexithymia). Employing a proof-of-concept design, the aim of the present study is to test the feasibility and acceptability of a novel, blended psychoeducation and digital mHealth (mobile health) intervention with smartphones designed to target alexithymia and poor social functioning to reduce suicide risk in Veterans with SMI.


Eligibility

Min Age: 18 Years

Inclusion Criteria8

  • a DSM-V diagnosis of PTSD
  • bipolar disorder
  • MDD
  • schizophrenia
  • at risk of suicide(Columbia Suicide Severity Rating Scale
  • C-SSRS \>=3 or a suicide attempt in the past 5 years)
  • limited emotion awareness (Toronto Alexithymia Scale; TAS-20 \>=52)
  • can understand all the study's risks and benefits

Exclusion Criteria3

  • have medical/neurological conditions that could interfere with study participation
  • enrolled in another treatment study
  • unable/unwilling to provide a verifiable contact for emergency purposes

Interventions

BEHAVIORALAffective Awareness

Intervention involving psychoeducation and daily emotion awareness practices


Locations(1)

James J. Peters VA Medical Center, Bronx, NY

The Bronx, New York, United States

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NCT05724953


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