Phase 1 Bladder Carcinoma Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1Phase 2

In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

Non-Muscle Invasive Bladder CarcinomaStage 0a Bladder Cancer AJCC v8Stage 0is Bladder Cancer AJCC v8+1 more
Mayo Clinic40 enrolled1 locationNCT06704191
Recruiting
Phase 1

Adaptive RADiation Therapy With Concurrent Sacituzumab Govitecan (SG) for Muscle Invasive Bladder Cancer

Muscle-Invasive Bladder CarcinomaLocalized Muscle Invasive Bladder Urothelial Carcinoma
Shilpa Gupta, MD20 enrolled1 locationNCT05833867
Recruiting
Phase 1

Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases

Intrahepatic CholangiocarcinomaGallbladder CarcinomaMetastatic Malignant Neoplasm in the Peritoneum+5 more
City of Hope Medical Center12 enrolled1 locationNCT05285358
Recruiting
Phase 1

PLZ4-Coated Paclitaxel-Loaded Micelles for the Treatment of Patients With Recurrent or Refractory Non-Muscle Invasive Bladder Cancer

Stage 0a Bladder Cancer AJCC v8Stage 0is Bladder Cancer AJCC v8Stage I Bladder Cancer AJCC v8+1 more
University of California, Davis12 enrolled1 locationNCT06173349
Recruiting
Phase 1Phase 2

Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer

Muscle-Invasive Bladder CarcinomaBladder CancerStage II Bladder Cancer AJCC v8+1 more
University of California, San Francisco47 enrolled1 locationNCT06470282
Recruiting
Phase 1

Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

Muscle-Invasive Bladder CarcinomaGastroesophageal Adenocarcinoma
Washington University School of Medicine32 enrolled1 locationNCT06529822
Recruiting
Phase 1

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers

Breast CarcinomaUrothelial CarcinomaOvarian Carcinoma+31 more
Jonsson Comprehensive Cancer Center30 enrolled1 locationNCT07118176
Recruiting
Phase 1Phase 2

RC48 Combined with Toripalimab As Neoadjuvant Therapy for Cisplatin Ineligible MIBC Patients

Muscle-Invasive Bladder CarcinomaBladder Cancer
Zhujiang Hospital55 enrolled1 locationNCT06341400