Phase 1 Brain Cancer Clinical Trials
8 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–8 of 8 trials
Recruiting
Phase 1Phase 2
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
Brain CancerGBMGlioma+12 more
National Institute of Neurological Disorders and Stroke (NINDS)40 enrolled1 locationNCT07416188
Recruiting
Phase 1Phase 2
Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM
CancerBrain TumorBrain Cancer+6 more
Northwell Health67 enrolled1 locationNCT03213002
Recruiting
Phase 1Phase 2
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
Brain TumorBrain CancerGlioblastoma+4 more
Northwell Health33 enrolled1 locationNCT02861898
Recruiting
Phase 1
18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery
Brain Metastases, AdultBrain MetastasesBrain Cancer
Baptist Health South Florida46 enrolled1 locationNCT06048094
Not Yet Recruiting
Phase 1
PaedNeoVax - A phase I clinical trial to assess safety and efficacy of personalised mRNA vaccine for children and young adults with high-risk brain tumours
Brain Cancer
Australian and New Zealand Children's Haematology Oncology Group10 enrolled1 locationACTRN12626000585325
Recruiting
Phase 1
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery
Brain Metastases, AdultBrain MetastasesBrain Cancer
Baptist Health South Florida20 enrolled1 locationNCT04689048
Recruiting
Phase 1
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.
Brain TumorBrain CancerGlioblastoma+6 more
Henry Ford Health System18 enrolled1 locationNCT05686798
Recruiting
Phase 1Phase 2
TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas
Brain MetastasesBrain TumorBrain Cancer+4 more
Essen Biotech85 enrolled1 locationNCT06640582