Phase 1 Brain Injury Clinical Trials
12 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–12 of 12 trials
Recruiting
Phase 1
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
ImpulsivitySuicidal IdeationMild Traumatic Brain Injury
VA Office of Research and Development55 enrolled1 locationNCT05647044
Recruiting
Phase 1Phase 2
Low-Tech Treatments for Obstructive Sleep Apnea
Traumatic Brain Injury (TBI)Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences60 enrolled1 locationNCT07301710
Recruiting
Phase 1
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Mild Traumatic Brain InjuryHeadacheBrain Concussion+1 more
State University of New York - Upstate Medical University60 enrolled1 locationNCT06112093
Recruiting
Phase 1
Combinatory Rehabilitation Used for Substantially Helping Individuals With Traumatic Brain Injury
Traumatic Brain Injury
Kessler Foundation60 enrolled1 locationNCT05716048
Not Yet Recruiting
Phase 1
A First in Human, Randomized, Double-Blind, Placebo-Controlled, Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of TT20 Administered Intravenously as Single Dose Infusions and Continuous Infusions in Healthy Adult Volunteers
Neonatal Brain Injury
Tellus Therapeutics72 enrolled1 locationACTRN12625000892415
Recruiting
Phase 1Phase 2
Safety and Efficacy of Angiotensin (1-7) in Persons With Moderate to Severe Traumatic Brain Injury
Traumatic Brain Injury
University of Arizona90 enrolled1 locationNCT06282965
Recruiting
Phase 1
Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury
Traumatic Brain InjurySubarachnoid Hemorrhage
University of Maryland, Baltimore15 enrolled1 locationNCT06103201
Recruiting
Phase 1
Regulation of Emotion, Sleep Extension, and mTBI
Mild Traumatic Brain Injury
Merrimack College60 enrolled1 locationNCT06883006
Recruiting
Phase 1Phase 2
Evaluating the Effect of Tranexamic Acid on the Clinical Outcomes in Patients With Traumatic Brain Injury
Traumatic Brain Injury
Mansoura University90 enrolled1 locationNCT06330935
Recruiting
Phase 1
Cord blood therapy in premature babies: a safety and feasibility study
preterm brain injury
Monash Health20 enrolled1 locationACTRN12619001637134
Terminated
Phase 1
A 15-Day, Single-blind, Placebo Controlled Food Safety and Tolerability Study of AXA3359 in Adult Subjects with Mild Traumatic Brain Injury (mTBI)
Otherwise healthy individuals with mild Traumatic Brain InjuryConcussion
Axcella Health Inc.30 enrolled1 locationACTRN12618001341213
Withdrawn
Phase 1
Repeatability and diurnal variation of eye responses measured with Neuro-Ophthalmic Device (NODe)
epilepsy or any type of seizureMild traumatic brain injury (mTBI) or concussionmedically diagnosed psychiatric disorder
Percy Lazon de la Jara20 enrolled1 locationACTRN12615000371594