Brain Injury Clinical Trials

14 recruiting

Brain Injury Trials at a Glance

293 actively recruiting trials for brain injury are listed on ClinicalTrialsFinder across 6 cities in 39 countries. The largest study group is Not Applicable with 143 trials, with the heaviest enrollment activity in Minneapolis, Boston, and Houston. Lead sponsors running brain injury studies include VA Office of Research and Development, University of Minnesota, and Kessler Foundation.

Browse brain injury trials by phase

Treatments under study

About Brain Injury Clinical Trials

Looking for clinical trials for Brain Injury? There are currently 14 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Brain Injury trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Brain Injury clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 293 trials

Recruiting
Not Applicable

Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.

Traumatic Brain Injury
NYU Langone Health150 enrolled1 locationNCT04349852
Recruiting
Not Applicable

Implementation of a Home-based Computerized Cognitive Rehabilitation Program for Patients With ABI

Acquired Brain Injury (Including Stroke)
Erasmus Medical Center30 enrolled1 locationNCT06749197
Recruiting

A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

Traumatic Brain Injury
Hoffmann-La Roche2,000 enrolled12 locationsNCT07455136
Recruiting
Not Applicable

Feasibility of Web-based Therapy Sessions

Cognitive ImpairmentAcquired Brain InjurySpeech Dysfunction
Liverpool University Hospitals NHS Foundation Trust80 enrolled1 locationNCT07560696
Recruiting
Not Applicable

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

SleepMild Traumatic Brain InjurySleep Architecture+1 more
University of Missouri-Columbia15 enrolled1 locationNCT07385105
Recruiting
Not Applicable

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

DepressionMild Traumatic Brain InjuryConcussion, Brain
University of California, San Diego72 enrolled1 locationNCT05682677
Recruiting
Not Applicable

Non-invasive BCI-controlled Assistive Devices

Traumatic Brain InjuryHealthyMovement Disorders+6 more
University of Texas at Austin100 enrolled1 locationNCT05183152
Recruiting
Not Applicable

Effect of Semi-elemental Enteral Nutrition on Gastrointestinal Tolerance in Patients With Traumatic Brain Injury.

Traumatic Brain InjuryNeurocritical CareEnteral Feeding Intolerance
Tang-Du Hospital100 enrolled1 locationNCT07092423
Recruiting
Not Applicable

rTMS for Military TBI-related Depression

Depressive SymptomsConcussionMild Traumatic Brain Injury
Henry M. Jackson Foundation for the Advancement of Military Medicine198 enrolled3 locationsNCT05426967
Recruiting

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

TBITBI (Traumatic Brain Injury)Hemodynamic Instability+1 more
Children's Hospital Los Angeles1,000 enrolled1 locationNCT06195345
Recruiting

Evaluation of the SCALED (SCaling AcceptabLE cDs)

Traumatic Brain InjuryVenous Thromboembolism
University of Minnesota15,000 enrolled1 locationNCT05628207
Recruiting
Not Applicable

SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury

Severe Traumatic Brain InjuryTraumatic Brain Injury (TBI) Patients
Stony Brook University80 enrolled1 locationNCT07560631
Recruiting
Not Applicable

Clinical Investigation to Validate the Safety and Performance of Integrating Functional Electrical Stimulation Into the ABLE Exoskeleton

Multiple SclerosisSpinal Cord InjuryAcquired Brain Injury (Including Stroke)
ABLE Human Motion S.L.15 enrolled1 locationNCT07550699
Recruiting
Not Applicable

Improving Cognitive Rehabilitation Outcomes

Mild Traumatic Brain InjuryPosttraumatic Stress Disorder
VA Office of Research and Development144 enrolled2 locationsNCT07055633
Recruiting

Neural Mechanism of Cerebrocardiac Syndrome Following Traumatic Brain Injury

Traumatic Brain InjuryCerebrocardiac Syndrome
Shanghai 6th People's Hospital90 enrolled2 locationsNCT06958406
Recruiting
Phase 4

Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

Traumatic Brain Injury
Wake Forest University Health Sciences600 enrolled1 locationNCT06866691
Recruiting
Not Applicable

Balance After Traumatic Brain Injury

Traumatic Brain Injury
VA Office of Research and Development70 enrolled1 locationNCT05714150
Recruiting
Not Applicable

External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial

Severe Traumatic Brain InjuryIntracranial Hypertension
Brain Trauma Foundation30 enrolled6 locationsNCT05889650
Recruiting

Long Lasting Effect of Hyperbaric Oxygen Therapy on Cognitive Function in Traumatic Brain Injury Patients

TBI (Traumatic Brain Injury)
Assaf-Harofeh Medical Center100 enrolled1 locationNCT07430150
Recruiting

Selective CT for Anticoagulated Head Injured Patients

Traumatic Brain InjuryHead InjuryIntracranial Hemorrhage, Traumatic+1 more
Dr. Kerstin de Wit4,000 enrolled7 locationsNCT05364749