Phase 2 Breast Neoplasms Clinical Trials
20 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 20 trials
Recruiting
Phase 2
A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
Metastatic Breast CancerBreast NeoplasmsGastroesophageal Junction Adenocarcinoma+7 more
Seagen, a wholly owned subsidiary of Pfizer172 enrolled139 locationsNCT06157892
Recruiting
Phase 2
Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
Breast CancerBreast Neoplasms
Merck Sharp & Dohme LLC372 enrolled17 locationsNCT06797635
Recruiting
Phase 2
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Breast CancerBreast NeoplasmsHER2-negative Breast Cancer+6 more
QuantumLeap Healthcare Collaborative5,000 enrolled42 locationsNCT01042379
Recruiting
Phase 2Phase 3
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
Breast Neoplasms
Bristol-Myers Squibb500 enrolled293 locationsNCT06926868
Recruiting
Phase 1Phase 2
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Breast CancerBreast Neoplasms
Pfizer100 enrolled159 locationsNCT06966453
Recruiting
Phase 1Phase 2
Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
Breast CancerBreast Neoplasms
Merck Sharp & Dohme LLC81 enrolled17 locationsNCT06686394
Recruiting
Phase 2
Tirzepatide Weight Loss for MRD+ Early Breast Cancer
Breast CancerBreast NeoplasmsBreast Cancers
Baylor Research Institute48 enrolled1 locationNCT06517212
Recruiting
Phase 1Phase 2
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Phase 1Phase 2
Target-specific immunoPET Imaging of Breast Cancer
Breast CancerBreast Cancer MetastaticBreast Neoplasms
RenJi Hospital200 enrolled1 locationNCT06715826
Recruiting
Phase 2
(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer
Breast NeoplasmsInvasive Breast Cancer
Atossa Therapeutics, Inc.87 enrolled15 locationsNCT05607004
Recruiting
Phase 2
Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM
Breast NeoplasmsLung Neoplasms
Brown University60 enrolled1 locationNCT06974604
Recruiting
Phase 2
A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study
Breast NeoplasmsOvarian Neoplasms
GlaxoSmithKline30 enrolled25 locationsNCT04641247
Recruiting
Phase 2
18F-FDG Versus 68Ga-FAPI-46 as PET Tracer in ER-positive Breast Cancer.
Breast CancerBreast NeoplasmsBreast Diseases
Maastricht University Medical Center20 enrolled1 locationNCT06335069
Recruiting
Phase 2
Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score
Breast CancerBreast NeoplasmsCancer of the Breast+1 more
Washington University School of Medicine50 enrolled1 locationNCT02476786
Recruiting
Phase 2
Randomized Phase II Trial: Chest Wall RT Omission After Prosthetic Reconstruction
Breast Neoplasms
Second Affiliated Hospital, School of Medicine, Zhejiang University152 enrolled1 locationNCT06464913
Recruiting
Phase 2
Trilaciclib in Patients With Early-Stage HR-negative Breast Cancer Receiving Adjuvant Chemotherapy
Breast Neoplasms
wang shusen116 enrolled1 locationNCT05978648
Recruiting
Phase 1Phase 2
Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer
Breast Neoplasms
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University196 enrolled1 locationNCT05981014
Recruiting
Phase 1Phase 2
Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer
Breast Neoplasms
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University170 enrolled1 locationNCT05981001
Recruiting
Phase 2
Efficacy and Safety of Pyrotinib Maleate Combined With ARX788 Neoadjuvant Treatment in Breast Cancer Patients
Breast Neoplasms
Shengjing Hospital30 enrolled1 locationNCT04983121
Recruiting
Phase 2
Circulating Tumor Cells and Treatment De-escalation After Neoadjuvant Therapy for HER2 Positive Breast Cancer
Breast NeoplasmsHER2-positive Breast CancerCirculating Tumor Cell
AC Camargo Cancer Center80 enrolled1 locationNCT04993014