Early Phase 1 Breast Clinical Trials

33 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 120 of 33 trials

Recruiting
Early Phase 1

3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer

Breast Carcinoma
Mayo Clinic55 enrolled1 locationNCT05704283
Recruiting
Early Phase 1

First-in-human Diagnostic Imaging Profile of the Theranostic Pair [68Ga]Ga-DOTA-STR-17126 and Low Dose [177Lu] Lu-DOTA-STR-17126 in Patients With Advanced or Metastatic Cancer

Metastatic Breast CancerCancerMetastatic Prostate Cancer+5 more
Integrated Haematology and Oncology Network20 enrolled1 locationNCT07608848
Recruiting
Early Phase 1

Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI)

Triple-Negative Breast Cancer
University of Alabama at Birmingham20 enrolled1 locationNCT04861077
Recruiting
Early Phase 1

MUSE-S Headband System for Improving Anxiety and Insomnia Among Breast Cancer Survivors

Breast Carcinoma
Mayo Clinic20 enrolled1 locationNCT06274034
Recruiting
Early Phase 1

Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast Cancer

TNBC - Triple-Negative Breast CancerLocally Advanced Triple Negative Breast Cancer
Rima Patel15 enrolled1 locationNCT06637306
Recruiting
Early Phase 1

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

Metastatic CancerHER2Locally Advanced Cancer+2 more
Vanderbilt-Ingram Cancer Center30 enrolled1 locationNCT06828588
Recruiting
Early Phase 1

Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms

Breast CancerAromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)Joint Pain
Philip Chang30 enrolled2 locationsNCT06123286
Recruiting
Early Phase 1

Window Study of Intratumoral Mitazalimab in Breast Cancer (WINIT-BC)

Breast Cancer
Jennifer Zhang32 enrolled1 locationNCT07319195
Recruiting
Early Phase 1

Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy

Breast CancerTriple-Negative Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute16 enrolled1 locationNCT06435351
Recruiting
Early Phase 1

Breast Cancer PSMA PET

Triple-Negative Breast Cancer
Ahmad Shariftabrizi30 enrolled1 locationNCT06586047
Recruiting
Early Phase 1

Feasibility Evaluation of the Muse Magnetic Resonance Guided Focused Ultrasound System

Breast Cancer
University of Utah34 enrolled1 locationNCT05291507
Recruiting
Early Phase 1

Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+20 more
Ohio State University Comprehensive Cancer Center50 enrolled1 locationNCT05417308
Recruiting
Early Phase 1

FES BPET-DBT in Newly Diagnosed Breast Cancer

Breast Cancer
Abramson Cancer Center at Penn Medicine20 enrolled1 locationNCT05659797
Recruiting
Early Phase 1

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

Endometrial CancerNon-small Cell Lung CancerTNBC - Triple-Negative Breast Cancer+6 more
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06305962
Recruiting
Early Phase 1

Bortezomib Followed by Pembrolizumab and Cisplatin in metTNBC

Breast Cancer
Baylor Research Institute20 enrolled1 locationNCT04265872
Recruiting
Early Phase 1

B-GLUCANCER2 : A Pilot Study Evaluating a New Method for Cancer Detection by Measuring the Activity of Different Glycosidase Enzymes in the Plasma of Patients With a Localized Cancer.

Breast CancerPancreatic CancerPulmonary Cancer+4 more
Poitiers University Hospital220 enrolled1 locationNCT07236177
Recruiting
Early Phase 1

Positron Emission Tomography (PET) Imaging With Zirconium-89 (89Zr)-Trastuzumab for Prediction of HER2 Targeted Therapy Effectiveness

Breast Cancer
University of Alabama at Birmingham10 enrolled1 locationNCT03321045
Recruiting
Early Phase 1

Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy

Breast CancerLymphoma
University of Oklahoma104 enrolled2 locationsNCT05921253
Recruiting
Early Phase 1

Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer

Breast CancerTriple-Negative Breast CancerHER2-positive Breast Cancer+3 more
Alison Stopeck30 enrolled1 locationNCT06220214
Recruiting
Early Phase 1

A Prospective, Open-label, Single-arm, Exploratory Clinical Trial to Evaluate the Safety and Tolerability of 225Ac-TR2205 Injection in Patients With Triple-negative Breast Cancer.

Advanced Metastatic Triple-negative Breast Cancer (mTNBC)
Xiaorong Sun15 enrolled1 locationNCT07340424