Phase 1 Bronchiectasis Clinical Trials

6 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 16 of 6 trials

Recruiting
Phase 1Phase 2

A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

Chronic Obstructive Pulmonary DiseaseNon-cystic Fibrosis Bronchiectasis
Genentech, Inc.128 enrolled7 locationsNCT06603246
Recruiting
Phase 1Phase 2

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Bronchiectasis
Chiesi Farmaceutici S.p.A.45 enrolled9 locationsNCT06166056
Recruiting
Phase 1

A Clinical Study of RSS0343 in Healthy Subjects

Non-cystic Fibrosis Bronchiectasis
Reistone Biopharma Company Limited48 enrolled1 locationNCT07289464
Completed
Phase 1

Inhalation of Leukotriene B4 (LTB4) in patients suffering from Bronchiectasis

BronchiectasisChronic Suppurative Lung Disease
LTB4 Sweden AB30 enrolled1 locationACTRN12614001199606
Not Yet Recruiting
Phase 1

Nicotinamide and innate immunity in patients with bronchiectasis

Bronchiectasis
Dr Conroy Wong, Middlemore Hospital8 enrolled1 locationACTRN12613000699763
Completed
Phase 1

A single dose, 3-way cross-over study comparing the safety, tolerability and pharmacokinetics of two inhaled Liposomal Ciprofloxacin Hydrochloride (HCl) for Inhalation formulations in two different nebulizers in healthy adults, with single dose assessment in subjects with non-Cystic Fibrosis (CF) bronchiectasis.

Non-Cystic Fibrosis (CF) bronchiectasis
Aradigm Corporation15 enrolled1 locationACTRN12609000544279