Cancer Clinical Trials in Toronto, Ontario

319 recruitingToronto, Ontario, Canada

Showing 120 of 319 trials

Recruiting
Phase 3

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Triple-Negative Breast Cancer
Merck Sharp & Dohme LLC1,530 enrolled299 locationsNCT06393374
Recruiting
Phase 2

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

Breast Cancer Metastatic
ALX Oncology Inc.120 enrolled44 locationsNCT07007559
Recruiting
Phase 3

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

Locally Advanced (Inoperable) or Metastatic Breast Cancer
AstraZeneca895 enrolled284 locationsNCT04862663
Recruiting
Phase 3

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Breast Cancer (Early Breast Cancer)
AstraZeneca4,300 enrolled711 locationsNCT05774951
Recruiting
Phase 2

Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer

Breast Cancer
Canadian Cancer Trials Group484 enrolled10 locationsNCT05601440
Recruiting
Not Applicable

Positron Emission Mammography and Liquid Biopsy in Women With High-risk Breast Screenings

Breast Cancer
University Health Network, Toronto100 enrolled1 locationNCT06268405
Recruiting

Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host

Breast CancerBreast NeoplasmsColorectal, Cancer+3 more
University Health Network, Toronto120 enrolled1 locationNCT02732860
Recruiting
Phase 1Phase 2

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Advanced HR+/HER2- Breast CancerAdvanced CCNE1-amplified Solid Tumors
Novartis Pharmaceuticals280 enrolled33 locationsNCT06726148
Recruiting
Phase 3

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

Breast CancerMetastatic Breast CancerHER2-Negative Breast Carcinoma+2 more
Olema Pharmaceuticals, Inc.510 enrolled233 locationsNCT06016738
Recruiting

CfDNA in Hereditary And High-risk Malignancies 2

Hereditary Cancer Syndrome
University Health Network, Toronto1,000 enrolled8 locationsNCT06726642
Recruiting

Short-term Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer

Breast Cancer Females
University of Toronto40 enrolled1 locationNCT06781762
Recruiting
Phase 3

Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position

Breast CancerRadiation Dermatitis
Sunnybrook Health Sciences Centre276 enrolled1 locationNCT06915857
Recruiting
Phase 2

Safety of Continuing HER-2 Directed Therapy in Overt Left Ventricular Dysfunction

Breast CancerHeart Failure
Population Health Research Institute130 enrolled8 locationsNCT04680442
Recruiting
Not Applicable

The Role of Stereo-tActic BoDy RadIotherApy iN Oligo-Progressive MalignanT Disease

MalignancyBreast Cancer MetastaticGenito-urinary
University Health Network, Toronto130 enrolled1 locationNCT04122469
Recruiting

Genomic Investigation of Unusual Responders

Breast CancerColorectal, CancerCancer+8 more
University Health Network, Toronto100 enrolled1 locationNCT03740503
Recruiting

Chronic Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer

Breast Cancer Females
University of Toronto112 enrolled1 locationNCT06776458
Recruiting

Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery

Breast Cancer
University of Toronto50 enrolled1 locationNCT04616300
Recruiting
Not Applicable

Remote Monitoring of Patient Reported Outcomes to Improve the Efficacy of the Acute Phase Radiotherapy Review Process

Breast CancerProstate Cancer
University Health Network, Toronto124 enrolled1 locationNCT06274892
Recruiting
Phase 1

MRI-Guided Ultrasound Stimulated Microbubbles Radiation Treatment for Patients with Chest-Wall and Locally Advanced Breast Cancer

Breast Cancer
Sunnybrook Health Sciences Centre30 enrolled1 locationNCT06633601
Recruiting
Not Applicable

Use of Quantitative Ultrasound to Guide Adaptive Chemotherapy Among Women With Breast Cancer

Breast Cancer
Sunnybrook Health Sciences Centre240 enrolled1 locationNCT04050228