Phase 1 Cardiac Clinical Trials
16 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–16 of 16 trials
Recruiting
Phase 1
Test-retest Study With [18F]FBB in Cardiac Amyloidosis
Cardiac Amyloidosis
Life Molecular Imaging GmbH15 enrolled2 locationsNCT06790394
Recruiting
Phase 1Phase 2
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children
Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Phase 1
Post-CA Neuroprotection With Magnesium
Cardiac ArrestReturn of Spontaneous Circulation
NYU Langone Health178 enrolled1 locationNCT06455514
Recruiting
Phase 1
Packed Red Blood Cell Transfusion During Cardiac Arrest
Cardiac Arrest
NYU Langone Health30 enrolled1 locationNCT06462027
Recruiting
Phase 1
Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia
CardiomyopathiesFriedreich AtaxiaMyocardial Fibrosis+1 more
Weill Medical College of Cornell University25 enrolled1 locationNCT05302271
Recruiting
Phase 1
Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation
Cardiac Arrest Neonatal
University of Alberta20 enrolled1 locationNCT05738148
Recruiting
Phase 1
A Study to Evaluate the Effect of Single Oral Dose of Balinatunfib on Cardiac Repolarization in Healthy Adult Participants.
Healthy VolunteersCardiac Repolarization
Sanofi44 enrolled2 locationsNCT07272629
Recruiting
Phase 1
Fish Oil, Metformin and Heart Health in PCOS
Cardiovascular DiseasePCOSAtherosclerotic Plaque+2 more
University of Alberta146 enrolled3 locationsNCT06424860
Recruiting
Phase 1
Hydrogen's Feasibility and Safety as a Therapy in ECPR
Cardiac ArrestExtracorporeal Membrane OxygenationReperfusion Injury
Boston Children's Hospital53 enrolled4 locationsNCT05574296
Completed
Phase 1
Effect of ONC201 on Cardiac Repolarization in Healthy Participants - Part 1
CancerSolid TumoursAbnormal cardiac repolarization
Chimerix, Inc.6 enrolled1 locationACTRN12622001021763
Completed
Phase 1
Effect of ONC201 on Cardiac Repolarization in Healthy Participants - Part 2
CancerSolid TumoursAbnormal cardiac repolarization
Chimerix, Inc.30 enrolled1 locationACTRN12622001020774
Completed
Phase 1
A Phase 1 Study of a Novel Bi-Directional Arterial Cannula in Patients requiring Peripheral Cannulation for Cardiac Surgery.
Patients who require peripheral cannulation for cardiac surgery.
Alfred Hospital15 enrolled1 locationACTRN12615001008516
Completed
Phase 1
A Phase I Randomised, Double-Blind, Placebo-Controlled Dose Escalating Study of the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses of Oral NP202 in Adult Healthy Volunteers
Cardiac remodelling post acute myocardial infarction
NeuProtect Pty Ltd64 enrolled1 locationACTRN12614000479606
Not Yet Recruiting
Phase 1
Impact of pacemaker on cardiac function
Pacemaker lead implantationCardiac FunctionHeart Block
University of Adelaide, Centre for Heart Rhythm Disorder180 enrolled1 locationACTRN12613000461796
Completed
Phase 1
Effect of methoxyflurane on cardiac function in healthy male and female adults
Effects on Cardiac QT/QTc Interval of an intervention that is used for pain relief.
Medical Developments International39 enrolled1 locationACTRN12613000305729
Completed
Phase 1
Effect of SYR-472 on Cardiac Function in Healthy Adults
Effects on Cardiac QT/QTc Interval
Takeda Pharmaceutical Company Limited260 enrolled1 locationACTRN12610000292077