RecruitingPhase 1NCT06424860

Fish Oil, Metformin and Heart Health in PCOS

Dietary Fish Oil and Metformin Intervention for Heart Health in PCOS

Sponsor

University of Alberta

Enrollment

146 participants

Start Date

Nov 1, 2025

Study Type

INTERVENTIONAL

Conditions

Cardiovascular Disease PCOS Atherosclerotic Plaque Atherosclerotic Cardiovascular Disease Cardiac Hypertrophy

Summary

Women with Polycystic Ovary Syndrome (PCOS) have high testosterone levels which is associated with altered insulin-glucose metabolism and an adverse blood lipid profile, predisposing them to the development of Type II Diabetes and Cardiovascular Disease (CVD). This study will investigate the use of dietary fish oil supplementation as a safe and effective intervention, and as an adjunct therapy to standard of care treatment with metformin to improve heart health, blood lipids and insulin-glucose metabolism in women with PCOS, and those with PCOS and Type 2 Diabetes.

Eligibility

Sex: FEMALEMin Age: 25 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Fish Oil and Metformin, Fish oil, and others for people with atherosclerotic cardiovascular disease, atherosclerotic plaque, and other related conditions. The study is currently recruiting participants at 3 locations. People eligible for this study include women aged 25 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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