Phase 2 Cardiac Clinical Trials

41 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 41 trials

Recruiting
Phase 2

Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.

Cardiac Arrest
Centre Hospitalier de Bethune234 enrolled14 locationsNCT05817851
Recruiting
Phase 2

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery

Acute Kidney InjuryCardiac Surgery
Arch Biopartners Inc.240 enrolled9 locationsNCT05879432
Recruiting
Phase 2Phase 3

Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care

Out of Hospital Cardiac Arrest (OHCA)
Siriraj Hospital318 enrolled1 locationNCT07239908
Recruiting
Phase 1Phase 2

Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children

Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Phase 2

Repurposing Tilmanocept for Cardiac Sarcoidosis

Cardiac Sarcoidosis
Duke University15 enrolled1 locationNCT07159074
Recruiting
Phase 2

Factor VIII Inhibitor Bypass Activity (FEIBA) Versus Fresh Frozen Plasma As First Line Therapy For Bleeding After Cardiac Surgery

SurgeryCardiac DiseaseBleeding
Northwell Health140 enrolled1 locationNCT07032792
Recruiting
Phase 2

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

Coronary Artery Bypass Grafting (CABG)Cardiopulmonary BypassIntensive Care Unit+9 more
GCP-Service International West GmbH550 enrolled10 locationsNCT06279793
Recruiting
Phase 2Phase 3

Early Double Sequential Defibrillation in Out of Hospital Cardiac Arrest

sudden deathVentricular FibrillationOut-of-hospital cardiac arrest+3 more
Gabriel Riva916 enrolled14 locationsNCT07174986
Recruiting
Phase 2

Post-operative Intravenous Iron to Treat Iron-deficiency Anemia in Patients Undergoing Cardiac Surgery

Cardiac SurgeryChronic Iron Deficiency Anaemia
University Health Network, Toronto60 enrolled3 locationsNCT06287619
Recruiting
Phase 2

StereoTactic Arrhythmia Radiotherapy in the NetherLands no. 2

Ventricular TachycardiaArrythmia, Cardiac
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)12 enrolled1 locationNCT05439031
Recruiting
Phase 2

Delayed Cold-Stored Platelets -PLTS-1

BleedingCardiac SurgeryCardiopulmonary Bypass+1 more
University Health Network, Toronto150 enrolled2 locationsNCT06147531
Recruiting
Phase 2

Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients

Breast CancerHeart FailureAnthracycline-induced Cardiac Toxicity+2 more
University Medical Centre Ljubljana100 enrolled1 locationNCT07245069
Recruiting
Phase 2

Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted

Early Stage Breast CancerCardiac Toxicity
Rutgers, The State University of New Jersey60 enrolled10 locationsNCT05559164
Recruiting
Phase 2

CardioPulmonary Resuscitation With Argon (CPAr) Trial

Cardiac Arrest, Out-Of-HospitalCardiac Arrest With Successful Resuscitation
Mario Negri Institute for Pharmacological Research120 enrolled9 locationsNCT05482945
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of BX-001N in Preventing Cardiac Surgery-Associated Acute Kidney Injury (CSA-AKI) and Major Adverse Kidney Events (MAKE)

Cardiac Surgery associated Acute kidney injuryIschemia Reperfusion Injury
Bilix Co.,Ltd.40 enrolled5 locationsNCT07164833
Recruiting
Phase 2

Rilonacept in Subjects With Cardiac Sarcoidosis

Cardiac Sarcoidosis
Mayo Clinic60 enrolled2 locationsNCT06660732
Recruiting
Phase 2

Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial

Heart FailureMyocardial InfarctionCoronary Artery Bypass+2 more
Baystate Medical Center320 enrolled2 locationsNCT05925634
Not Yet Recruiting
Phase 2

The NIKI-C Study - A study of plasma pharmacokinetics of nebulized ketamine in post cardiac surgery patients.

Post-operative intensive care.Intensive Care Cardiac Surgery
University of Queensland20 enrolled1 locationACTRN12625000579493
Recruiting
Phase 2

Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage

Cardiac FailureCerebral InfarctionCerebral Ischemia+3 more
Turku University Hospital160 enrolled7 locationsNCT04696523
Recruiting
Phase 2Phase 3

POHCA Resuscitation: Evaluation of IM Epinephrine

Pediatric Out-of-Hospital Cardiac Arrest
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's284 enrolled1 locationNCT05166343