Cardiomyopathy Clinical Trials in Cleveland, Ohio
20 recruitingCleveland, Ohio
Showing 1–20 of 20 trials
Recruiting
Phase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals1,250 enrolled207 locationsNCT07052903
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company582 enrolled98 locationsNCT06563895
Recruiting
Phase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Transthyretin Amyloidosis (ATTR) With Cardiomyopathy
Intellia Therapeutics1,200 enrolled132 locationsNCT06128629
Recruiting
Phase 1Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Hypertrophic Cardiomyopathy
Tenaya Therapeutics30 enrolled10 locationsNCT05836259
Recruiting
HCMR Re-Imaging Study
Hypertrophic Cardiomyopathy (HCM)
Christopher Kramer314 enrolled8 locationsNCT07054073
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic CardiomyopathyObstructive Cardiomyopathy, Hypertrophic
Lexicon Pharmaceuticals500 enrolled107 locationsNCT06481891
Recruiting
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables
Congenital Heart DiseasePregnancy RelatedCongenital Vascular Disorder+1 more
The Cleveland Clinic50 enrolled1 locationNCT06818760
Recruiting
Not Applicable
Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients Who Present With Symptomatic Heart Failure With Reduced Ejection Fraction (HFrEF): The CORCINCH-HF Study
Heart Failure With Reduced Ejection Fraction (HFrEF)Dilated Cardiomyopathy
Ancora Heart, Inc.400 enrolled132 locationsNCT04331769
Recruiting
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
Cardiac AmyloidosisCardiomyopathy, HypertrophicLumbar Spinal Stenosis+3 more
Columbia University1,663 enrolled6 locationsNCT06034405
Recruiting
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb1,600 enrolled99 locationsNCT05489705
Recruiting
Phenotypic Classification of FMR With CMR
Functional Mitral RegurgitationIschemic CardiomyopathyNonischemic Congestive Cardiomyopathy
The Cleveland Clinic360 enrolled1 locationNCT05965258
Recruiting
Not Applicable
Left vs Left Randomized Clinical Trial
Heart FailureHeart Failure With Reduced Ejection FractionPacing-Induced Cardiomyopathy+4 more
Baylor College of Medicine2,136 enrolled71 locationsNCT05650658
Recruiting
Phase 4
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy
Peripartum Cardiomyopathy, Postpartum
Dennis M. McNamara, MD, MS250 enrolled64 locationsNCT05180773
Recruiting
A Cardiac Disease Quality of Life Study
Quality of LifeHypertrophic Obstructive CardiomyopathyThoracic Aortic Dilatation+1 more
The Cleveland Clinic1,200 enrolled1 locationNCT04080492
Recruiting
Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers
Amyloidosis CardiacAmyloidosis, HereditaryAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center500 enrolled3 locationsNCT05489549
Recruiting
Development of CIRC Technologies
Heart FailureCardiovascular DiseasesAtrial Fibrillation+7 more
The Cleveland Clinic1,000 enrolled1 locationNCT05654272
Recruiting
International Consortium for Multimodality Phenotyping in Adults With Non-compaction
Non-Compaction Cardiomyopathy
Stanford University600 enrolled5 locationsNCT04424030
Recruiting
Phase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Arrhythmogenic Right Ventricular Cardiomyopathy
Tenaya Therapeutics15 enrolled7 locationsNCT06228924
Recruiting
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
Cardiomyopathy
Tenaya Therapeutics200 enrolled29 locationsNCT05112237
Recruiting
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Arrhythmogenic Right Ventricular Cardiomyopathy
Tenaya Therapeutics200 enrolled21 locationsNCT06311708