Phase 4 Care Clinical Trials
20 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 20 trials
Recruiting
Phase 4
Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
PainCleft PalatePerioperative Care+2 more
Duke University60 enrolled1 locationNCT06962306
Recruiting
Phase 4
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
CardiovascularRed Blood Cell TransfusionsSex Differences+3 more
Michelle Zeller11,082 enrolled8 locationsNCT06840756
Recruiting
Phase 4
CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS
Critical IllnessCritical Care, Intensive CareFluid and Electrolyte Imbalance+2 more
University Hospital, Antwerp640 enrolled4 locationsNCT07189091
Recruiting
Phase 4
Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU Patients
Older PatientsEsketamineDexmedetomidine+3 more
Peking University First Hospital100 enrolled1 locationNCT07151716
Recruiting
Phase 4
Oral vs IV Sedation for Cataract Surgery in Older Adults
Older AdultsSedationPerioperative Care+2 more
University of California, San Francisco20 enrolled1 locationNCT07154147
Recruiting
Phase 4
Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia
Pain ManagementPostoperative CareAnalgesic Drugs+3 more
Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology100 enrolled1 locationNCT07070050
Recruiting
Phase 4
Pulsed Electromagnetic Field Therapy or Pneumatic Compression VTE Prophylaxis
Intensive Care MedicineVenous ThromboembolismVenous Thromboembolism (VTE)
Science Valley Research Institute50 enrolled1 locationNCT06958588
Recruiting
Phase 4
Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent Implantation
Perioperative CareAntiplatelet Agents
Kyoto University1,200 enrolled1 locationNCT06723145
Recruiting
Phase 4
Beta-Lactam Antibiotics InitiaL ExpoSure OptimisEd in CriticallY Ill Patients with SEpsis
SepsisSeptic ShockSepsis - to Reduce Mortality in the Intensive Care Unit
Erasmus Medical Center980 enrolled1 locationNCT06766461
Recruiting
Phase 4
Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patients
AnalgesiaDexmedetomidineMechanical Ventilation+2 more
The First Affiliated Hospital with Nanjing Medical University100 enrolled1 locationNCT05466708
Not Yet Recruiting
Phase 4
Safety of anticoagulation in elective colonoscopy
Elective colonoscopyThromboembolismPeri-procedural care
Dr Nicholas Tutticci200 enrolled1 locationACTRN12621001644853
Completed
Phase 4
Duration of Pertussis Immunity in Adults: a study of Healthcare Workers.
A study analysing the duration of Immunity to Pertussis booster vaccine in Health Care workers to establish guidelines when boosters are required.
Telethon Kids Institute150 enrolled1 locationACTRN12615001262594
Not Yet Recruiting
Phase 4
Does disinfection of Intensive Care Unit rooms with Hydrogen Peroxide Vapour, in adults, compared to standard disinfection practices, is equivalent to, or reduce the transmission to patients of Clostridium difficile and multi-resistant organisms?
Intensive Care Unit room cleaning impact on transmission of organisms.
Dr Bruce Seidel800 enrolled1 locationACTRN12614000034639
Recruiting
Phase 4
Dexmedetomidine pharmacodynamics and population pharmacokinetics in elderly intensive care unit (ICU) patients
Intensive Care patients aged 65 and more
Noorjahan Haneem binti Md Hashim60 enrolled1 locationACTRN12612000892819
Completed
Phase 4
Tramadol administration in the critically ill
Intensive Care Unit (ICU) Step Down patients who require patient controlled analgesia (PCA) Fentanyl as part of their management after trauma or surgery.
Guy Ludbrook15 enrolled1 locationACTRN12611001018909
Completed
Phase 3Phase 4
A prospective, open-label, daily wear, parallel group, randomised clinical trial assessing an investigational contact lens care solution for comfort, safety and efficacy with four commercially available contact lenses, worn bilaterally over three months, in both experienced and new contact lens wearers
Contact lens care solutionContact lens wear
Abbott Medical Optics, Inc160 enrolled1 locationACTRN12609000640202
Completed
Phase 3Phase 4
Crystalloid versus Hydroxy-Ethyl Starch Trial - A multi-centre randomized controlled trial of fluid resuscitation with starch (6% hydroxyl starch 130/0/4) compared to saline (0.9%) sodium chloride in intensive care patients on mortality.
Fluid resuscitation in intensive care patients
The George Institute for Global Health7,000 enrolled2 locationsACTRN12609000245291
Recruiting
Phase 4
Optimising cefepime dosing in intensive care: the pharmacokinetics of extended (prolonged) infusions.
intensive care sepsis
The Alfred30 enrolled1 locationACTRN12609000069257
Completed
Phase 4
A General Practitioner intervention on frequent attenders
Frequent attendance in Primary Health Care
Juan Angel Bellon210 enrolledACTRN12607000266460
Recruiting
Phase 4
Economic and Social Benefits of Treating and Preventing Influenza in Aged Care Facilities
Influenza outbreak in an aged-care facility
The University of Sydney3,200 enrolled1 locationACTRN12606000278538