Phase 1 Chemotherapy Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 17 of 7 trials

Recruiting
Phase 1Phase 2

A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy
Novartis Pharmaceuticals123 enrolled2 locationsNCT07226986
Recruiting
Phase 1Phase 2

Ramucirumab (Cyramza), Nal-IRI (ONIVYDE) and Trifluridine/Tipiracil (Lonsurf) in Second Line Metastatic Gastric Cancer .

ChemotherapyMetastatic Gastric AdenocarcinomaSecond Line
National Health Research Institutes, Taiwan45 enrolled1 locationNCT05927857
Recruiting
Phase 1

Randomized Trial of Glutathione With Anti-PD-1 and Chemotherapy in Advanced NSCLC

ChemotherapyNon-small Cell Lung CancerPD1 Antibody+1 more
The First Affiliated Hospital of Zhengzhou University80 enrolled1 locationNCT06896422
Recruiting
Phase 1Phase 2

Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer

Cervical CancerImmunotherapyInduction Chemotherapy
Tianjin Medical University Cancer Institute and Hospital20 enrolled1 locationNCT06093438
Recruiting
Phase 1

Study of IBI363 in Patients with Advanced First-line Gastric Cancer

IBI363 + Chemotherapy
Xiangdong Cheng40 enrolled1 locationNCT06610799
Recruiting
Phase 1

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA

Breast CancerColorectal, CancerOvarian Cancer+7 more
Lebanese University50 enrolled2 locationsNCT06307249
Recruiting
Phase 1Phase 2

The Efficacy of JS001 Combined With Chemotherapy in Patients With Locally Advanced Colon Cancer

Chemotherapy EffectColonic Neoplasms
Xiangya Hospital of Central South University40 enrolled1 locationNCT03985891