Phase 3 Chemotherapy Clinical Trials
52 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 52 trials
Recruiting
Phase 3
Trial of a Virtual Exercise-based Rehabilitation Program to Treat Persistent Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Chemotherapy-induced Peripheral Neuropathy (CIPN)
University Health Network, Toronto240 enrolled1 locationNCT07481149
Recruiting
Phase 3
Olanzapine in the Prevention and Treatment of Anorexia-Cachexia Syndrome in Patients Receiving Neoadjuvant/Preoperative Chemotherapy
OncologyCachexia-Anorexia SyndromeOncology Patients Receiving Chemotherapy
Blokhin's Russian Cancer Research Center100 enrolled1 locationNCT07633236
Recruiting
Phase 2Phase 3
Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.
Radiotherapy Side EffectNeoadjuvant TherapyChemotherapy+8 more
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos400 enrolled1 locationNCT06758830
Recruiting
Phase 3
IC Plus Low-dose Radiation Plus Cadonilimab in LANPC
ChemotherapyRadiotherapyImmune Checkpoint Inhibitor+1 more
Sun Yat-sen University380 enrolled3 locationsNCT05941741
Recruiting
Phase 3
Study on the Efficacy and Safety of Mecobalamin in Preventing Taxane-related Peripheral Neuropathy
Peripheral Neuropathy Due to ChemotherapyPeripheral Neuropathy, Chemotherapy-induced
Qinghai Red Cross Hospital326 enrolled4 locationsNCT07423390
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia
Patients With Chemotherapy-Induced Thrombocytopenia
Jiangsu HengRui Medicine Co., Ltd.150 enrolled7 locationsNCT07286032
Recruiting
Phase 3
Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy
Chemotherapy Induced Peripheral Neuropathy
Institut Cancerologie de l'Ouest274 enrolled11 locationsNCT05840562
Recruiting
Phase 3
Neoadjuvant Treatment Modalities in Esophageal Cancer
Esophageal CancerSurgeryChemotherapy Effect+4 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled1 locationNCT04821843
Recruiting
Phase 3
Chemoradiotherapy in Esophageal or Esophagogastric Junction Cancer
Esophagus CancerChemotherapy EffectTargeted Therapy+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled5 locationsNCT04821778
Recruiting
Phase 3
Adjuvant Oxaliplatin Plus S-1 Versus Docetaxel Plus S-1 for Stage III Gastric Cancer
Gastric Cancer (GC)Adjuvant ChemotherapyOxaliplatin+2 more
Ruijin Hospital387 enrolled5 locationsNCT07366528
Recruiting
Phase 3
Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC
Weight LossNeoadjuvant Chemotherapy
Sixth Affiliated Hospital, Sun Yat-sen University60 enrolled1 locationNCT06998758
Recruiting
Phase 3
Camrelizumab and Apatinib With or Without FOLFOX Chemotherapy for Advanced HCC
Chemotherapy EffectHepato Cellular Carcinoma (HCC)
Linhui Peng326 enrolled1 locationNCT07267806
Recruiting
Phase 3
Electroacupuncture for Chemotherapy-Induced GI Symptom Clusters in Breast Cancer
Standard Quadruple Antiemetic TherapyElectroacupunctureChemotherapy-induced Gastrointestinal Symptom Cluster
Jiuda Zhao388 enrolled1 locationNCT06952920
Recruiting
Phase 3
Infusional FOLFOX Plus Camrelizumab and Apatinib vs HAIC-FOLFOX Plus Camrelizumab and Apatinib for Advanced HCC
Chemotherapy EffectBCLC Stage C Hepatocellular Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University262 enrolled1 locationNCT06172205
Recruiting
Phase 3
Benefit of Transcutaneous Auricular Vagus Nerve Stimulation in Improving Quality of Life in First Line Treatment of Ovarian Cancer:
Ovarian CarcinomaFirst Line ChemotherapyDigestive System Disorders
Centre Francois Baclesse116 enrolled4 locationsNCT06817161
Recruiting
Phase 2Phase 3
Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ)
Chemotherapy Induced Peripheral NeuropathyPain SyndromePain, Neuropathic
Bernardino Clavo, MD, PhD42 enrolled2 locationsNCT04299893
Recruiting
Phase 3
Clinical Trial With Aconite Pain Oil in Oncology Patients Under Chemotherapy to Prevent CIPN Grade-II, to Reduce Symptoms and to Improve the Quality of Life of Patients With CIPN
Chemotherapy-induced Polyneuropathy
WALA Heilmittel GmbH350 enrolled1 locationNCT06186479
Recruiting
Phase 3
GM1 Prophylaxis for Nab-paclitaxel-associated Chemotherapy-induced Peripheral Neuropathy (CIPN) in Patients With Breast Cancer
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Qilu Pharmaceutical Co., Ltd.352 enrolled1 locationNCT06994507
Recruiting
Phase 3
Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma
Neoadjuvant TherapyAdjuvant ChemotherapyGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+3 more
Zuoyi Jiao668 enrolled4 locationsNCT06949033
Recruiting
Phase 2Phase 3
Total Neoadjuvant FLOT Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Cancer
Gastric CancerChemotherapyGastroesophageal Junction Adenocarcinoma+13 more
Ukrainian Society of Clinical Oncology150 enrolled2 locationsNCT06028737