Phase 3 Chemotherapy Clinical Trials

39 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 39 trials

Recruiting
Phase 3

Study on the Efficacy and Safety of Mecobalamin in Preventing Taxane-related Peripheral Neuropathy

Peripheral Neuropathy Due to ChemotherapyPeripheral Neuropathy, Chemotherapy-induced
Qinghai Red Cross Hospital326 enrolled4 locationsNCT07423390
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia

Patients With Chemotherapy-Induced Thrombocytopenia
Jiangsu HengRui Medicine Co., Ltd.150 enrolled7 locationsNCT07286032
Recruiting
Phase 3

IC Plus Low-dose Radiation Plus Cadonilimab in LANPC

ChemotherapyRadiotherapyImmune Checkpoint Inhibitor+1 more
Sun Yat-sen University380 enrolled3 locationsNCT05941741
Recruiting
Phase 3

Neoadjuvant Treatment Modalities in Esophageal Cancer

Esophageal CancerSurgeryChemotherapy Effect+4 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled1 locationNCT04821843
Recruiting
Phase 3

Chemoradiotherapy in Esophageal or Esophagogastric Junction Cancer

Esophagus CancerChemotherapy EffectTargeted Therapy+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled5 locationsNCT04821778
Recruiting
Phase 3

Adjuvant Oxaliplatin Plus S-1 Versus Docetaxel Plus S-1 for Stage III Gastric Cancer

Gastric Cancer (GC)Adjuvant ChemotherapyOxaliplatin+2 more
Ruijin Hospital387 enrolled5 locationsNCT07366528
Recruiting
Phase 3

Megestrol Acetate in Improving Neoadjuvant Chemotherapy-Related Weight Loss in Locally Advanced CRC

Weight LossNeoadjuvant Chemotherapy
Sixth Affiliated Hospital, Sun Yat-sen University60 enrolled1 locationNCT06998758
Recruiting
Phase 3

Camrelizumab and Apatinib With or Without FOLFOX Chemotherapy for Advanced HCC

Chemotherapy EffectHepato Cellular Carcinoma (HCC)
Linhui Peng326 enrolled1 locationNCT07267806
Recruiting
Phase 3

Electroacupuncture for Chemotherapy-Induced GI Symptom Clusters in Breast Cancer

Standard Quadruple Antiemetic TherapyElectroacupunctureChemotherapy-induced Gastrointestinal Symptom Cluster
Jiuda Zhao388 enrolled1 locationNCT06952920
Recruiting
Phase 3

Infusional FOLFOX Plus Camrelizumab and Apatinib vs HAIC-FOLFOX Plus Camrelizumab and Apatinib for Advanced HCC

Chemotherapy EffectBCLC Stage C Hepatocellular Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University262 enrolled1 locationNCT06172205
Recruiting
Phase 3

Benefit of Transcutaneous Auricular Vagus Nerve Stimulation in Improving Quality of Life in First Line Treatment of Ovarian Cancer:

Ovarian CarcinomaFirst Line ChemotherapyDigestive System Disorders
Centre Francois Baclesse116 enrolled4 locationsNCT06817161
Recruiting
Phase 3

Clinical Trial With Aconite Pain Oil in Oncology Patients Under Chemotherapy to Prevent CIPN Grade-II, to Reduce Symptoms and to Improve the Quality of Life of Patients With CIPN

Chemotherapy-induced Polyneuropathy
WALA Heilmittel GmbH350 enrolled1 locationNCT06186479
Recruiting
Phase 3

GM1 Prophylaxis for Nab-paclitaxel-associated Chemotherapy-induced Peripheral Neuropathy (CIPN) in Patients With Breast Cancer

Chemotherapy-induced Peripheral Neuropathy (CIPN)
Qilu Pharmaceutical Co., Ltd.352 enrolled1 locationNCT06994507
Recruiting
Phase 3

Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Neoadjuvant TherapyAdjuvant ChemotherapyGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+3 more
Zuoyi Jiao668 enrolled4 locationsNCT06949033
Recruiting
Phase 3

Neoadjuvant Apatinib Combined With Sintilimab and Perioperative SOX Versus Neoadjuvant Sintilimab Combined With Perioperative SOX for Intestinal Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Neoadjuvant TherapyAdjuvant ChemotherapyGastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ])+3 more
Zuoyi Jiao682 enrolled4 locationsNCT06925243
Recruiting
Phase 3

Olanzapine Versus Placebo for Moderately Emetogenic Chemotherapy

Chemotherapy Induced Nausea and Vomiting
Mahidol University140 enrolled1 locationNCT06850454
Recruiting
Phase 2Phase 3

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Radiotherapy Side EffectNeoadjuvant TherapyChemotherapy+8 more
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos400 enrolled1 locationNCT06758830
Recruiting
Phase 3

Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC

SurgeryPancreas CancerNeoadjuvant Chemotherapy+3 more
Sahlgrenska University Hospital432 enrolled1 locationNCT06714604
Recruiting
Phase 3

NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer)

Neoadjuvant ChemotherapyResectable Pancreatic CancerEffects of Chemotherapy
Seoul National University Hospital609 enrolled2 locationsNCT05529940
Recruiting
Phase 3

Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC

Hepatocellular CarcinomaChemotherapy EffectChemotherapeutic Toxicity
Sun Yat-sen University540 enrolled1 locationNCT06041477