Phase 2 Childhood Clinical Trials
35 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 35 trials
Recruiting
Phase 2
N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma
NeuroblastomaHigh Risk NeuroblastomaChildhood Neuroblastoma
Memorial Sloan Kettering Cancer Center45 enrolled1 locationNCT06528496
Recruiting
Phase 2Phase 3
Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol
Childhood Leukemia, Acute LymphoblasticB-cell Acute Lymphoblastic Leukemia (B-ALL)Acute Lymphoblastic Leukemia ALL
Institute of Hematology & Blood Diseases Hospital, China1,800 enrolled27 locationsNCT06764238
Recruiting
Phase 2
Phentermine's Impact on Treatment in Teens
Childhood Obesity
Russell McCulloh, MD240 enrolled2 locationsNCT07282340
Recruiting
Phase 1Phase 2
CANnabinoids in Pediatric ONCology
CancerChildhood Cancer
University of Manitoba60 enrolled3 locationsNCT05754840
Recruiting
Phase 1Phase 2
Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors
GliomaCNS Tumor, AdultCNS Tumor, Childhood
Centre Leon Berard70 enrolled12 locationsNCT07243470
Recruiting
Phase 1Phase 2
Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRefractory Childhood Malignant Solid Neoplasm+6 more
Children's Oncology Group81 enrolled21 locationsNCT06620302
Recruiting
Phase 1Phase 2
Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML
Acute Myeloid LeukemiaAMLAML, Childhood+1 more
Washington University School of Medicine68 enrolled1 locationNCT06158828
Recruiting
Phase 1Phase 2
Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders
Juvenile Myasthenia GravisANCA Associated Vasculitis (AAV)Juvenile Dermatomyositis+1 more
Cartesian Therapeutics50 enrolled2 locationsNCT07089121
Recruiting
Phase 2
Povidone Iodine Efficacy Study
Early childhood caries
University of Rochester202 enrolled1 locationNCT05272254
Recruiting
Phase 2
Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma
Liver CancerFibrolamellar CarcinomaHepatocellular Carcinoma, Childhood+1 more
Allison O'Neill, MD18 enrolled5 locationsNCT04134559
Recruiting
Phase 2
A Study to Give Treatment Inside the Eye to Treat Retinoblastoma
Unilateral RetinoblastomaBilateral RetinoblastomaChildhood Intraocular Retinoblastoma+2 more
Children's Oncology Group26 enrolled20 locationsNCT05504291
Recruiting
Phase 2
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Burkitt Lymphoma/Leukemia, or Double-Hit Lymphoma/Leukemia
Refractory Acute Lymphoblastic LeukemiaRecurrent Acute Lymphoblastic LeukemiaRecurrent Adult Lymphoblastic Lymphoma+8 more
M.D. Anderson Cancer Center42 enrolled1 locationNCT03136146
Recruiting
Phase 1Phase 2
Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma
SarcomaSolid Tumor, AdultSolid Tumor, Childhood
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins39 enrolled4 locationsNCT03465592
Recruiting
Phase 1Phase 2
Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia
ALL, Childhood B-CellAcute Lymphoid Leukemia RelapseAcute Lymphocytic Leukemia Refractory
University Hospital Tuebingen20 enrolled11 locationsNCT05366218
Recruiting
Phase 1Phase 2
Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer
Refractory CancerRecurrent CancerChildhood Cancer+2 more
Australian & New Zealand Children's Haematology/Oncology Group90 enrolled14 locationsNCT06208657
Recruiting
Phase 2Phase 3
Food-Body-Mind Intervention (16 Weeks)
Obesity, ChildhoodMental Health WellnessSocial Skills+2 more
Michigan State University800 enrolled1 locationNCT06597474
Recruiting
Phase 2Phase 3
Newly-diagnosed Pediatric T-cell ALL Protocol
Acute Lymphoblastic LeukemiaChildhood Leukemia, Acute LymphoblasticT Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Institute of Hematology & Blood Diseases Hospital, China610 enrolled27 locationsNCT06855810
Recruiting
Phase 2Phase 3
Newly-diagnosed Low Risk Pediatric B-cell ALL Protocol
Childhood Leukemia, Acute LymphoblasticB-cell Acute Lymphoblastic Leukemia (B-ALL)Acute Lymphoblastic Leukemia ALL
Institute of Hematology & Blood Diseases Hospital, China3,000 enrolled27 locationsNCT06882057
Recruiting
Phase 1Phase 2
Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates.
Intestinal microbiomeMicrobiotaGastrointestinal Microbiome+3 more
National Institute of Allergy and Infectious Diseases (NIAID)600 enrolled1 locationNCT03298334
Recruiting
Phase 2
Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease
Non-Alcoholic Fatty Liver DiseaseImpaired Glucose ToleranceType 2 Diabetes Mellitus+1 more
Yale University60 enrolled1 locationNCT05067621