Childhood Clinical Trials

294 recruitingLast updated: May 13, 2026

There are 294 actively recruiting childhood clinical trials across 58 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, Houston, Texas, United States, St Louis, Missouri, United States. Updated daily from ClinicalTrials.gov.


Childhood Trials at a Glance

294 actively recruiting trials for childhood are listed on ClinicalTrialsFinder across 6 cities in 58 countries. The largest study group is Not Applicable with 130 trials, with the heaviest enrollment activity in New York, Houston, and St Louis. Lead sponsors running childhood studies include St. Jude Children's Research Hospital, Children's Oncology Group, and Guangzhou Women and Children's Medical Center.

Treatments under study

About Childhood Clinical Trials

Looking for clinical trials for Childhood? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Childhood trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Childhood clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 294 trials

Recruiting
Phase 4

Pediatric Long-Term Follow-up and Rollover Study

Neurofibromatosis Type 1GlioblastomaAnaplastic Astrocytoma+20 more
Novartis Pharmaceuticals165 enrolled55 locationsNCT03975829
Recruiting
Not Applicable

Oral Health Intervention for Caregivers of Children Presenting for Dental Surgery

Early childhood caries
University of Illinois at Chicago420 enrolled1 locationNCT07220850
Recruiting

Genetic Disorders of Obesity Program Database

Genetic DiseaseObesity, Childhood
Baylor College of Medicine500 enrolled1 locationNCT05747976
Recruiting

DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

Diabetes Mellitus Type 2, Childhood-Onset
George Washington University3,600 enrolled20 locationsNCT06525259
Recruiting
Not Applicable

Time Restricted Eating in Childhood Obesity (TRECO)

Childhood Obesity
Xiaoyan Shi128 enrolled2 locationsNCT06583447
Recruiting
Not Applicable

Effects of Blowing Balloon Therapy FUNCTION, DYSPNEA AND QUALITY OF LIFE IN OBESE CHILDREN

Obesity, Childhood
Riphah International University38 enrolled1 locationNCT07576478
Recruiting

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

InfertilityAcute Ovarian FailureEarly Menopause And Infertility In Females After Treatment For Childhood Cancer
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)100 enrolled1 locationNCT05440617
Recruiting
Phase 3

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Childhood Medulloblastoma
Children's Oncology Group225 enrolled105 locationsNCT05382338
Recruiting
Phase 1

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group54 enrolled20 locationsNCT06894979
Recruiting
Phase 3

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Germ Cell TumorChildhood Extracranial Germ Cell TumorExtragonadal Embryonal Carcinoma+27 more
Children's Oncology Group1,780 enrolled629 locationsNCT03067181
Recruiting

Project: Every Child for Younger Patients With Cancer

Malignant Solid NeoplasmNeuroendocrine NeoplasmCentral Nervous System Neoplasm+15 more
Children's Oncology Group75,000 enrolled278 locationsNCT02402244
Recruiting
Phase 1Phase 2

Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRefractory Childhood Malignant Solid Neoplasm+6 more
Children's Oncology Group81 enrolled21 locationsNCT06620302
Recruiting
Not Applicable

Questionnaire on Congenital Cancer Signs Through Self-Assessment

Pediatric CancerHereditary Cancer SyndromesCancer Predisposition Syndromes+1 more
Insel Gruppe AG, University Hospital Bern205 enrolled1 locationNCT07378423
Recruiting
Not Applicable

Asthma Link Effectiveness Trial

Childhood Asthma
University of Massachusetts, Worcester350 enrolled1 locationNCT06388460
Recruiting
Not Applicable

Feasibility of a Diet Intervention for Juvenile Arthritis

Juvenile Idiopathic ArthritisArthritis, JuvenileArthritis, Childhood
The Hospital for Sick Children54 enrolled7 locationsNCT06474546
Recruiting
Not Applicable

Reducing Obesity Through Play Among Toddlers: Tiny Steps to Health (TSHS) Study

Childhood Obesity
University of Houston300 enrolled1 locationNCT06918821
Recruiting
Phase 3

International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma

Lymphoblastic Lymphoma, Childhood
University Hospital Muenster683 enrolled228 locationsNCT04043494
Recruiting
Phase 1Phase 2

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

Acute Myeloid LeukemiaAMLAML, Childhood+1 more
Washington University School of Medicine68 enrolled1 locationNCT06158828
Recruiting
Not Applicable

Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program

Substance-Related DisordersAdverse Childhood Experiences
RTI International360 enrolled1 locationNCT06236100
Recruiting
Not Applicable

The Evira Study: Additional Support During Obesity Treatment

Childhood ObesityTreatment Adherence
Karolinska Institutet40 enrolled2 locationsNCT06836284