Childhood Clinical Trials

305 recruitingLast updated: July 25, 2026

There are 305 actively recruiting childhood clinical trials across 58 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, Memphis, Tennessee, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Childhood Trials at a Glance

305 actively recruiting trials for childhood are listed on ClinicalTrialsFinder across 6 cities in 58 countries. The largest study group is Not Applicable with 134 trials, with the heaviest enrollment activity in New York, Memphis, and Houston. Lead sponsors running childhood studies include St. Jude Children's Research Hospital, Children's Oncology Group, and Guangzhou Women and Children's Medical Center.

Treatments under study

About Childhood Clinical Trials

Looking for clinical trials for Childhood? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Childhood trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Childhood clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 305 trials

Recruiting
Phase 2

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

NeuroblastomaHigh Risk NeuroblastomaChildhood Neuroblastoma
Memorial Sloan Kettering Cancer Center45 enrolled1 locationNCT06528496
Recruiting
Phase 2Phase 3

Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol

Childhood Leukemia, Acute LymphoblasticB-cell Acute Lymphoblastic Leukemia (B-ALL)Acute Lymphoblastic Leukemia ALL
Institute of Hematology & Blood Diseases Hospital, China1,800 enrolled27 locationsNCT06764238
Recruiting
Not Applicable

Neural Mechanisms of Family-Focused Treatment for Youth Depression

Childhood Depression
Boston University Charles River Campus80 enrolled2 locationsNCT06289010
Recruiting
Phase 4

Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT Trial)

Lupus Nephritis (LN)Childhood-onset Systemic Lupus Erythematosus
Peking Union Medical College Hospital198 enrolled8 locationsNCT07719140
Recruiting
Not Applicable

Childhood Trauma, Exercise, and Cognition

Adverse Childhood Experiences
University of Texas at Austin34 enrolled1 locationNCT05972265
Recruiting

Assessing and Addressing Health-Related Social Needs Among Families of Children With Cancer

Caregiver social supportChildhood CancersCaregiver Distress+1 more
Wake Forest University Health Sciences60 enrolled1 locationNCT07278414
Recruiting

Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

InfertilityAcute Ovarian FailureEarly Menopause And Infertility In Females After Treatment For Childhood Cancer
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)100 enrolled1 locationNCT05440617
Recruiting
Phase 3

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Germ Cell TumorChildhood Extracranial Germ Cell TumorExtragonadal Embryonal Carcinoma+27 more
Children's Oncology Group1,780 enrolled629 locationsNCT03067181
Recruiting
Phase 3

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Childhood Medulloblastoma
Children's Oncology Group225 enrolled108 locationsNCT05382338
Recruiting

Quality of End-of-Life Care for Children With Cancer

Childhood Malignant Solid NeoplasmChildhood Hematopoietic and Lymphatic System Neoplasm
Children's Oncology Group2,425 enrolled15 locationsNCT07412002
Recruiting
Not Applicable

Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma

Childhood Cancer
St. Jude Children's Research Hospital188 enrolled1 locationNCT06747910
Recruiting

Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity

Childhood Obesity
Alder Hey Children's NHS Foundation Trust30 enrolled1 locationNCT07702825
Recruiting
Not Applicable

Early Life Exposures Among Children With Sickle Cell Disease

Sickle Cell DiseaseBreastfeedingAdverse Childhood Experiences
University of Alabama at Birmingham20 enrolled1 locationNCT05377372
Recruiting
Not Applicable

Resolving Early Life Stress: Psychotherapy Outcomes and Neurobiology in Complex Depression

Depression - Major Depressive DisorderChildhood Traumas
St. Joseph's Healthcare Hamilton50 enrolled1 locationNCT07250893
Recruiting
Early Phase 1

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

NeuroblastomaPineoblastomaAtypical Teratoid/Rhabdoid Tumor+11 more
C17 Council15 enrolled12 locationsNCT06942039
Recruiting
Not Applicable

Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies

Children with medical complexityTracheostomyFeeding Tube+1 more
University of Chicago40 enrolled1 locationNCT06525818
Recruiting
Not Applicable

Executive Function and Parenting in Childhood

Disruptive BehaviorExecutive FunctionDisruptive Behavior Disorder, Childhood Onset
University of Illinois at Chicago180 enrolled1 locationNCT06241300
Recruiting
Not Applicable

Digitally Delivered Child Obesity Prevention for Parents in Home Visiting Programs

Childhood Obesity Prevention
University of Florida50 enrolled1 locationNCT07230808
Recruiting

Healthy Weight Intervention Families During ALL Treatment: NOURISH-ALL

ALL, ChildhoodBehavior, Health
University of Kansas Medical Center46 enrolled2 locationsNCT06050850
Recruiting
Not Applicable

The Bottle Optimization Testing Tiny Little Eaters Study

Childhood Obesity
University of Michigan440 enrolled1 locationNCT07665983