Phase 3 Childhood Clinical Trials
21 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 21 trials
Recruiting
Phase 3
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
Germ Cell TumorChildhood Extracranial Germ Cell TumorExtragonadal Embryonal Carcinoma+27 more
Children's Oncology Group1,780 enrolled629 locationsNCT03067181
Recruiting
Phase 3
A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss
Childhood Medulloblastoma
Children's Oncology Group225 enrolled105 locationsNCT05382338
Recruiting
Phase 3
International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma
Lymphoblastic Lymphoma, Childhood
University Hospital Muenster683 enrolled228 locationsNCT04043494
Recruiting
Phase 3
Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour
Cognitive ImpairmentMedulloblastoma, Childhood
Donald Mabbott140 enrolled20 locationsNCT05230758
Recruiting
Phase 3
A Study to Test the Long-term Safety and Tolerability of Brivaracetam in Study Participants With Childhood Absence Epilepsy or Juvenile Absence Epilepsy
Childhood Absence EpilepsyJuvenile Absence Epilepsy
UCB Biopharma SRL120 enrolled23 locationsNCT06315322
Recruiting
Phase 3
An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors
Malignant Abdominal NeoplasmChildhood Malignant Solid NeoplasmChildhood Malignant Thoracic Neoplasm+3 more
Mayo Clinic20 enrolled1 locationNCT06915727
Recruiting
Phase 3
A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)
Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc.39 enrolled11 locationsNCT06760546
Recruiting
Phase 3
Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance
Insulin ResistanceObesity, Childhood
University of Alberta90 enrolled1 locationNCT04578652
Recruiting
Phase 2Phase 3
Food-Body-Mind Intervention (16 Weeks)
Obesity, ChildhoodMental Health WellnessSocial Skills+2 more
Michigan State University800 enrolled1 locationNCT06597474
Recruiting
Phase 3
Newly-diagnosed Pediatric Ph-positive B-ALL Protocol
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)Childhood Leukemia, Acute Lymphoblastic
Institute of Hematology & Blood Diseases Hospital, China150 enrolled24 locationsNCT07152041
Recruiting
Phase 2Phase 3
Newly-diagnosed Pediatric T-cell ALL Protocol
Acute Lymphoblastic LeukemiaChildhood Leukemia, Acute LymphoblasticT Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Institute of Hematology & Blood Diseases Hospital, China610 enrolled27 locationsNCT06855810
Recruiting
Phase 2Phase 3
Newly-diagnosed Low Risk Pediatric B-cell ALL Protocol
Childhood Leukemia, Acute LymphoblasticB-cell Acute Lymphoblastic Leukemia (B-ALL)Acute Lymphoblastic Leukemia ALL
Institute of Hematology & Blood Diseases Hospital, China3,000 enrolled27 locationsNCT06882057
Recruiting
Phase 3
Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents
Obesity, Childhood
Hospices Civils de Lyon68 enrolled4 locationsNCT03516968
Recruiting
Phase 3
Clinical Trial for Patients With a Stage IV Childhood Renal Tumor, Comparing Upfront Vincristine, Actinomycin-D and Doxorubicin (Standard Arm) With Upfront Vincristine, Carboplatin and Etoposide (Experimental Arm)
Childhood Renal Tumor
Assistance Publique Hopitaux De Marseille110 enrolled1 locationNCT03669783
Recruiting
Phase 2Phase 3
Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol
Childhood Leukemia, Acute LymphoblasticB-cell Acute Lymphoblastic Leukemia (B-ALL)Acute Lymphoblastic Leukemia ALL
Institute of Hematology & Blood Diseases Hospital, China1,800 enrolled26 locationsNCT06764238
Recruiting
Phase 2Phase 3
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma
Childhood Ependymoma
Centre Leon Berard536 enrolled40 locationsNCT02265770
Terminated
Phase 3
Initial Prednisolone Weaning in Nephrotic Syndrome: adrenal suppression and its association with relapse
Childhood Idiopathic Nephrotic SyndromeAdrenal gland suppression
Dr Amelia Le Page88 enrolled1 locationACTRN12621001428853
Active
Phase 3
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
Extragonadal SeminomaGerminomaCancer+9 more
Alliance for Clinical Trials in Oncology420 enrolled15 locationsACTRN12618001236280
Recruiting
Phase 3Phase 4
Rapid Iron Infusion Study- a randomised controlled trial (RCT) of the treatment of iron deficiency anaemia in children (RIIS)
Childhood Iron Deficiency Anaemia
Menzies School of Health Research226 enrolled2 locationsACTRN12617001273370
Not Yet Recruiting
Phase 3
The effect of an oral health education program for mothers and fluoride treatment on oral health in Indigenous Maori children
Early childhood caries
UNIVERSITY OF OTAGO200 enrolled1 locationACTRN12610000422022