Phase 2 Chronic Hepatitis Clinical Trials
33 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 33 trials
Recruiting
Phase 1Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Chronic Hepatitis Delta
Gilead Sciences200 enrolled19 locationsNCT07096193
Recruiting
Phase 1Phase 2
TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Michael Hoelscher81 enrolled6 locationsNCT06513286
Recruiting
Phase 2
VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B
Chronic Hepatitis B
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)50 enrolled1 locationNCT06092333
Recruiting
Phase 2
A Multicenter Study of AHB-137 Injection Combined With Other Hepatitis B Drugs
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.200 enrolled1 locationNCT07069569
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.60 enrolled1 locationNCT07137910
Recruiting
Phase 2
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Chronic Hepatitis B Infection
Aligos Therapeutics200 enrolled58 locationsNCT06963710
Recruiting
Phase 2Phase 3
Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide
Chronic Hepatitis D
Mirum Pharmaceuticals, Inc.120 enrolled22 locationsNCT07454837
Recruiting
Phase 2
A Study of Hydronidone Capsules in Patients With Chronic Hepatitis B Virus-Related Liver Fibrosis
Chronic Hepatitis B-related Liver Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.150 enrolled1 locationNCT07417553
Recruiting
Phase 2
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B
Gilead Sciences150 enrolled62 locationsNCT02932150
Recruiting
Phase 2
A Study to Evaluate the Safety of Hydronidone Capsules in Patients With Liver Fibrosis
Chronic Hepatitis B With Hepatic Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.200 enrolled1 locationNCT07364448
Recruiting
Phase 2
A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.30 enrolled1 locationNCT06993480
Recruiting
Phase 2
A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B
Chronic Hepatitis B
Fujian Shengdi Pharmaceutical Co., Ltd.369 enrolled1 locationNCT06425341
Recruiting
Phase 2
Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B
Chronic Hepatitis B
University of Maryland, Baltimore10 enrolled1 locationNCT06154278
Recruiting
Phase 2
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)
Anti-PD-1 AntibodyChronic Hepatitis BPeg-IFNα
The Second Affiliated Hospital of Chongqing Medical University120 enrolled1 locationNCT05771402
Recruiting
Phase 2
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A)
Anti-PD-1 AntibodyChronic Hepatitis B
The Second Affiliated Hospital of Chongqing Medical University120 enrolled1 locationNCT05769816
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of Combination Therapy of BRII-179, BRII-835 and PEG-IFNα in Participants With Chronic Hepatitis B Virus (HBV) Infection (ENHANCE)
Chronic Hepatitis B Virus (HBV) Infection
Brii Biosciences Limited250 enrolled14 locationsNCT06650852
Recruiting
Phase 2
A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B
Chronic Hepatitis B
Fujian Akeylink Biotechnology Co., Ltd.45 enrolled1 locationNCT06263959
Not Yet Recruiting
Phase 2
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Cavrotolimod in Subjects with Chronic Hepatitis B Infection
Chronic Hepatitis B Infection
Bluejay Therapeutics, Inc90 enrolled6 locationsACTRN12625000173493
Recruiting
Phase 1Phase 2
From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients
Chronic Hepatitis B
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)36 enrolled1 locationNCT06295328
Recruiting
Phase 2
A Clinical Trial to Evaluate the Efficacy and Safety of TQA3810 Tablets in Combination/Non Combination With Nucleoside (Acid) Analogues in Patients With Primary/Treated Chronic Hepatitis B
Chronic Hepatitis B
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.90 enrolled6 locationsNCT06566248