Phase 4 Chronic Clinical Trials
169 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 169 trials
Recruiting
Phase 4
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled61 locationsNCT07053423
Recruiting
Phase 4
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
Heart FailureChronic Lymphocytic Leukaemia
AstraZeneca60 enrolled23 locationsNCT06651970
Recruiting
Phase 4
Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients
Orthopaedic traumaChronic Opioid Use
Massachusetts General Hospital458 enrolled2 locationsNCT06201676
Recruiting
Phase 4
Asciminib Roll-over Study
Chronic Myelogenous LeukemiaLeukemia, Myelogenous, Chronic, BCR-ABL Positive
Novartis Pharmaceuticals347 enrolled84 locationsNCT04877522
Recruiting
Phase 4
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4
Better Options for Chronic Cancer Pain
Chronic PainCancer SurvivorOpioid Dependence
VA Office of Research and Development294 enrolled2 locationsNCT06574009
Recruiting
Phase 4
PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty
hip osteoarthritisHip ArthropathyHip Pain Chronic
Poznan University of Medical Sciences90 enrolled1 locationNCT07180979
Recruiting
Phase 4
Prospective Single-Arm Clinical Study of Thiotepa-Containing Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Chronic Myelomonocytic Leukemia
Chronic Myelomonocytic Leukemia (CMML)
Sun Yuqian31 enrolled1 locationNCT07588594
Recruiting
Phase 4
ASC22 Combined With Peg-IFNa in Achieving Functional Cure in Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B
The Second Affiliated Hospital of Chongqing Medical University150 enrolled1 locationNCT07573943
Recruiting
Phase 4
Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney Transplantation
Chronic Kidney Diseases
University of Erlangen-Nürnberg Medical School48 enrolled1 locationNCT06560801
Recruiting
Phase 4
Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression
Major Depressive DisorderChronic Major Depression, Recurrent
University of Texas at Austin50 enrolled1 locationNCT05892744
Recruiting
Phase 4
A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects
Chronic PancreatitisExocrine Pancreatic Insufficiency
Mayo Clinic24 enrolled1 locationNCT07285863
Recruiting
Phase 4
Effect of ZaStaprazan on Platelet Reactivity of Clopidogrel After PercuTaneous CoronAry InteRvention
Chronic Coronary Syndrome
Yonsei University100 enrolled1 locationNCT07471867
Recruiting
Phase 4
Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Adolescents With Early Stages of Chronic Kidney Disease
AdolescentAlbuminuriaSodium-glucose Co-transporter-2 Inhibitors+1 more
Centenario Hospital Miguel Hidalgo200 enrolled1 locationNCT07405216
Recruiting
Phase 4
Dex & Mastectomy Pain
Post-Mastectomy Chronic Pain Syndrome
McGill University Health Centre/Research Institute of the McGill University Health Centre170 enrolled1 locationNCT07556952
Recruiting
Phase 4
Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis
Chronic PancreatitisExocrine Pancreatic InsufficiencyRecurrent Acute Pancreatitis
Anna Evans Phillips80 enrolled2 locationsNCT07418593
Recruiting
Phase 4
Stanford Pragmatic Effectiveness Comparison
Chronic Pain
Stanford University450 enrolled1 locationNCT04441034
Recruiting
Phase 4
A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chronic Lymphocytic LeukemiaLymphoma, Small Lymphocytic
Eli Lilly and Company150 enrolled53 locationsNCT07218341
Recruiting
Phase 4
Empagliflozin Treatment in Kidney Transplant Recipients
Kidney TransplantChronic Kidney Disease
VA Office of Research and Development264 enrolled5 locationsNCT06013865
Recruiting
Phase 4
Low Dose Naltrexone for Pain in Patients With HIV
Human Immunodeficiency VirusChronic Neuropathic Pain
Emory University60 enrolled3 locationsNCT05537935