Phase 4 Chronic Clinical Trials
175 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 175 trials
Recruiting
Phase 4
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4
A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chronic Lymphocytic LeukemiaLymphoma, Small Lymphocytic
Eli Lilly and Company150 enrolled50 locationsNCT07218341
Recruiting
Phase 4
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
Chronic Obstructive Pulmonary Disease
Maria Joyera Rodríguez135 enrolled6 locationsNCT06334575
Recruiting
Phase 4
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency
Cholestatic Liver DiseaseChildrenVitamin D Deficiency+1 more
Chulalongkorn University54 enrolled1 locationNCT07670611
Recruiting
Phase 4
A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects
Chronic PancreatitisExocrine Pancreatic Insufficiency
Mayo Clinic24 enrolled1 locationNCT07285863
Recruiting
Phase 4
ASC22 Combined With Peg-IFNa in Achieving Functional Cure in Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B
The Second Affiliated Hospital of Chongqing Medical University150 enrolled1 locationNCT07573943
Recruiting
Phase 4
Asciminib Roll-over Study
Chronic Myelogenous LeukemiaLeukemia, Myelogenous, Chronic, BCR-ABL Positive
Novartis Pharmaceuticals347 enrolled85 locationsNCT04877522
Recruiting
Phase 4
Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant Women
Hepatitis B Virus - Chronic Active
ANRS, Emerging Infectious Diseases150 enrolled1 locationNCT05403047
Recruiting
Phase 4
Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2
ObesityChronic Kidney Disease
Western University, Canada60 enrolled1 locationNCT06396416
Recruiting
Phase 4
The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)
Chronic Heart FailureIron Deficiency, Latent
Tomsk National Research Medical Center of the Russian Academy of Sciences100 enrolled1 locationNCT05793996
Recruiting
Phase 4
Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis
DiabetesKidney Disease, ChronicEnd Stage Kidney Disease (ESRD)+1 more
Unity Health Toronto100 enrolled2 locationsNCT07017270
Recruiting
Phase 4
Study Title: A Multicenter, Prospective, Modified Platform Trial Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Matched Standard of Care Controls in the Management of Nonhealing Pressure Ulcers.
Skin UlcerPressure SorePressure Ulcer of Skin+3 more
Sequence LifeScience, Inc.2,000 enrolled1 locationNCT07665268
Recruiting
Phase 4
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
Heart FailureChronic Lymphocytic Leukaemia
AstraZeneca60 enrolled23 locationsNCT06651970
Recruiting
Phase 4
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled68 locationsNCT07053423
Recruiting
Phase 4
Biologics in Chronic Rhinosinusitis With Nasal Polyposis
Chronic SinusitisNasal Polyps
Medical University of South Carolina504 enrolled1 locationNCT06824649
Recruiting
Phase 4
Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease
Graft vs Host DiseaseChronic Graft vs. Host DiseaseCorticosteroid-refractory Chronic Graft vs. Host Disease
Novartis Pharmaceuticals50 enrolled22 locationsNCT06824103
Recruiting
Phase 4
A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia
InsomniaChronic InsomniaInsomnia Disorder+1 more
University of Pennsylvania1,200 enrolled1 locationNCT07542756
Recruiting
Phase 4
Safety of Short-course of NSAIDs in Pediatric Patients With CKD
Chronic Kidney DiseasePediatric Urology
University of Colorado, Denver164 enrolled1 locationNCT06860711
Recruiting
Phase 4
Dex & Mastectomy Pain
Post-Mastectomy Chronic Pain Syndrome
McGill University Health Centre/Research Institute of the McGill University Health Centre170 enrolled1 locationNCT07556952
Recruiting
Phase 4
Two Dose Levels of Privigen in Pediatric CIDP
Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
CSL Behring30 enrolled9 locationsNCT03684018