Chronic Clinical Trials

3,084 recruitingLast updated: July 25, 2026

There are 3,084 actively recruiting chronic clinical trials across 105 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include Houston, Texas, United States, New York, New York, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Chronic Trials at a Glance

3,084 actively recruiting trials for chronic are listed on ClinicalTrialsFinder across 6 cities in 105 countries. The largest study group is Not Applicable with 1,210 trials, with the heaviest enrollment activity in Houston, New York, and Boston. Lead sponsors running chronic studies include AstraZeneca, M.D. Anderson Cancer Center, and Mayo Clinic.

Treatments under study

About Chronic Clinical Trials

Looking for clinical trials for Chronic? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 3,084 trials

Recruiting
Phase 2

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

Chronic Myelogenous LeukemiaLeukemia, Myelogenous, Chronic, Philadelphia Chromosome Positive
Novartis Pharmaceuticals50 enrolled24 locationsNCT07354074
Recruiting

Chronic Subdural Hematoma Embolization With Detachable Coils

Chronic Subdural Hemorrhage (cSDH)
Icahn School of Medicine at Mount Sinai150 enrolled1 locationNCT07291427
Recruiting
Not Applicable

Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma

CancerObesityChronic Pain+3 more
University of Florida195 enrolled1 locationNCT05561595
Recruiting
Phase 3

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

CLLLeukemia, Lymphocytic, Chronic, B-CellLymphoma, Small Lymphocytic+3 more
Merck Sharp & Dohme LLC735 enrolled55 locationsNCT05947851
Recruiting
Not Applicable

AGE Accumulation in Patients on Long-term Parenteral Nutrition

parenteral nutritionChronic Intestinal InsufficiencyAdvanced Glycation and Products
University Hospital, Bordeaux50 enrolled3 locationsNCT07392801
Recruiting
Phase 2

Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)

Hematologic MalignanciesWaldenstroms MacroglobulinaemiaNon-Hodgkins Lymphoma+1 more
Merck Sharp & Dohme LLC490 enrolled121 locationsNCT04728893
Recruiting
Not Applicable

Effectiveness of DITM Versus IMT in COPD Patients

COPD, Chronic Obstructive Pulmonary Disease
Sir Run Run Shaw Hospital410 enrolled9 locationsNCT06958666
Recruiting
Phase 2

Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

Pain, ChronicSchwannomatosisSchwannomas
Massachusetts General Hospital40 enrolled1 locationNCT05684692
Recruiting
Phase 4

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation

Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 3

Mechanisms of Stimulation for Pain Alleviation

Chronic Neuropathic PainPeripheral Nerve StimulationChronic Neuropathic Pain (Below the Shoulders)
Stanford University148 enrolled2 locationsNCT06741579
Recruiting
Not Applicable

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

Heart FailureChronic Kidney DiseaseEnd-stage Kidney Disease
Cedars-Sinai Medical Center20 enrolled1 locationNCT06877169
Recruiting
Not Applicable

Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional Hypoxemia

Chronic Obstructive Pulmonary DiseaseInterstitial Lung DiseaseHypoxemia
State University of New York at Buffalo24 enrolled1 locationNCT07512687
Recruiting
Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
National Cancer Institute (NCI)247 enrolled631 locationsNCT04269902
Recruiting
Phase 3

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia
BeOne Medicines500 enrolled91 locationsNCT07277231
Recruiting
Phase 1Phase 2

Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors

Solid TumorsAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+6 more
Incyte Biosciences International Sàrl70 enrolled23 locationsNCT03934372
Recruiting
Not Applicable

NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities

Chronic Kidney DiseasesKidney Diseases
University of Colorado, Denver448 enrolled2 locationsNCT06810622
Recruiting
Not Applicable

The NTU JO-SMART Study

Obesity, OverweightChronic Kidney DiseaseDiabetes (DM)+1 more
National Taiwan University Hospital312 enrolled2 locationsNCT07317310
Recruiting
Not Applicable

Evaluation of Depression Screening Methods Administered by Registered Nurses in Chronic Hemodialysis Patients

Depressive DisordersEnd-stage Chronic Kidney Disease Treated With Hemodialysis
Centre Hospitalier Annecy Genevois450 enrolled2 locationsNCT07651436
Recruiting
Phase 3

Multi-Center Clean Air Randomized Controlled Trial in COPD

Chronic Obstructive Pulmonary Disease (COPD)
JHSPH Center for Clinical Trials770 enrolled11 locationsNCT06376994
Recruiting
Phase 1Phase 2

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaNon-Hodgkin Lymphoma+6 more
BeOne Medicines645 enrolled127 locationsNCT05006716