Chronic Clinical Trials

2,863 recruitingLast updated: May 21, 2026

There are 2,863 actively recruiting chronic clinical trials across 100 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include Boston, Massachusetts, United States, Houston, Texas, United States, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Chronic Trials at a Glance

2,863 actively recruiting trials for chronic are listed on ClinicalTrialsFinder across 6 cities in 100 countries. The largest study group is Not Applicable with 1,108 trials, with the heaviest enrollment activity in Boston, Houston, and New York. Lead sponsors running chronic studies include M.D. Anderson Cancer Center, Mayo Clinic, and VA Office of Research and Development.

About Chronic Clinical Trials

Looking for clinical trials for Chronic? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Chronic trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Chronic clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 2,863 trials

Recruiting
Phase 4

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled61 locationsNCT07053423
Recruiting
Not Applicable

Ultrasound and Respiratory Physiological Signals in Lung Diseases

UltrasoundChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease+5 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS25 enrolled1 locationNCT06068647
Recruiting
Phase 2

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaRichter Syndrome
Roswell Park Cancer Institute32 enrolled1 locationNCT06863402
Recruiting
Phase 3

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

Chronic Low Back Pain (CLBP)ObesityOverweight
Eli Lilly and Company586 enrolled40 locationsNCT07035093
Recruiting
Phase 2

Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

Recurrent Chronic Lymphocytic LeukemiaRecurrent Small Lymphocytic LymphomaRefractory Chronic Lymphocytic Leukemia+1 more
National Cancer Institute (NCI)20 enrolled6 locationsNCT07061951
Recruiting
Phase 1

Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

Recurrent Chronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic LeukemiaRecurrent Non-Hodgkin Lymphoma+15 more
Sumithira Vasu54 enrolled2 locationsNCT05418088
Recruiting
Phase 1

CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Recurrent Chronic Myelomonocytic LeukemiaRefractory Chronic Myelomonocytic LeukemiaRecurrent High Risk Myelodysplastic Syndrome+4 more
M.D. Anderson Cancer Center38 enrolled1 locationNCT03896269
Recruiting

American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)

Diabetes MellitusCardiovascular DiseasesChronic Kidney Diseases+1 more
University of New Mexico500 enrolled3 locationsNCT04185844
Recruiting
Phase 2

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Acute Myeloid LeukemiaMyelodysplastic SyndromeBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+11 more
M.D. Anderson Cancer Center508 enrolled1 locationNCT02115295
Recruiting
Phase 2

Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

Chronic Myeloid Leukemia
M.D. Anderson Cancer Center50 enrolled1 locationNCT06817720
Recruiting
Phase 2

A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Myelodysplastic SyndromeRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+3 more
M.D. Anderson Cancer Center76 enrolled1 locationNCT04239157
Recruiting
Not Applicable

Feasibility Study of a Digital Interactive Life-style Platform for Individuals After Rehabilitation

Acute Coronary SyndromeChronic Obstructive Pulmonary Disease (COPD)Fragility Fracture+1 more
Matthias Wilhelm, MD240 enrolled2 locationsNCT07597031
Recruiting

This is a Non-interventional, Study to Assess Demographic Characteristics and Patient Reported Outcomes in China Patients With SEA Treated With Benralizumab

Chronic Obstructive Pulmonary Disease
AstraZeneca1,000 enrolled36 locationsNCT06862206
Recruiting
Not Applicable

New Methods for Evaluating Preventive Migraine Treatment

MigraineHeadache DisordersChronic Migraine, Headache+1 more
University of Aarhus60 enrolled2 locationsNCT07071506
Recruiting
Not Applicable

Recovering From Bariatric Surgery: the Effects of Early Initiated and Supervised Mobilization

Bariatric SurgeryPhysical ActivityPostoperative Pain, Acute+2 more
Esbjerg Hospital - University Hospital of Southern Denmark112 enrolled1 locationNCT06222151
Recruiting

AQUALIS:QoL of CLL Patients Treated With Acalabrutinib in France, Retrospective Study Based on Data From PLATON Database

Chronic Lymphocytic Leukemia
AstraZeneca120 enrolled1 locationNCT06548152
Recruiting

A Registry for People With T-cell Lymphoma

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+27 more
Memorial Sloan Kettering Cancer Center1,000 enrolled26 locationsNCT05978141
Recruiting

Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study

Chronic Graft Versus Host Disease
Fred Hutchinson Cancer Center300 enrolled10 locationsNCT04431479
Recruiting
Phase 2

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Loxo Oncology, Inc.249 enrolled131 locationsNCT06588478
Recruiting
Not Applicable

Novel Treatment Delivery of ECAP-controlled Closed-loop SCS for Chronic Pain

Chronic Pain
Saluda Medical Pty Ltd200 enrolled25 locationsNCT04662905